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词条 Sophoradin
释义

  1. References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 426713434
| Name = Sophoradin
| ImageFile = Sophoradin.svg
| ImageSize = 200px
| ImageName = Chemical structure of sophoradin
| ImageAlt = Chemical structure of sophoradin
| IUPACName = (E)-1-[2,4-Dihydroxy-3-(3-methylbut-2-enyl)phenyl]-3-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]prop-2-en-1-one
| OtherNames = 2',4,4'-Trihydroxy-3,3',5-tris(3-methyl-2-butenyl)chalcone
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo = 23057-54-7
| CASNoOther =
| PubChem = 5321393
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4479146
| SMILES = O=C(c1ccc(O)c(c1O)C\\C=C(/C)C)\\C=C\\c2cc(c(O)c(c2)C/C=C(\\C)C)C\\C=C(/C)C
| InChI = 1/C30H36O4/c1-19(2)7-11-23-17-22(18-24(29(23)33)12-8-20(3)4)10-15-27(31)26-14-16-28(32)25(30(26)34)13-9-21(5)6/h7-10,14-18,32-34H,11-13H2,1-6H3/b15-10+
| InChIKey = YAPAFDNQABLIIN-XNTDXEJSBZ
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C30H36O4/c1-19(2)7-11-23-17-22(18-24(29(23)33)12-8-20(3)4)10-15-27(31)26-14-16-28(32)25(30(26)34)13-9-21(5)6/h7-10,14-18,32-34H,11-13H2,1-6H3/b15-10+
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = YAPAFDNQABLIIN-XNTDXEJSSA-N
| MeSHName =
}}
|Section2={{Chembox Properties
| C=30|H=36|O=4
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
}}
}}

Sophoradin is an isoprenyl chalconoid,[1] a type of polyphenolic compound, found in Sophora tonkinensis, an herb used in traditional Chinese medicine.

Sofalcone is an oral gastrointestinal medication and a synthetic analog of sophoradin.[2]

References

1. ^Synthesis of Isoprenyl Chalcone “Sophoradin” Isolated from Sophora subprostrata. Kazuaki Kyogoku, Katsuo Hatayama, Sadakazu Yokamori, Teruya Seki and Ichiro Tanaka, Agricultural and Biological Chemistry, Vol.39 , No.1(1975) pp.133-138
2. ^{{cite journal |vauthors=Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R |title=Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin |journal=Hepatogastroenterology |volume=34 |issue=4 |pages=164–70 |date=August 1987 |pmid=3478294 |doi= |url=}}
{{chalconoid}}{{phenol-stub}}

1 : Chalconoids

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