| 释义 |
- References
- Further reading
{{Infobox_gene}}Signal recognition particle receptor subunit beta is a protein that in humans is encoded by the SRPRB gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.[3]
}}References1. ^{{cite journal | vauthors = Miller JD, Tajima S, Lauffer L, Walter P | title = The beta subunit of the signal recognition particle receptor is a transmembrane GTPase that anchors the alpha subunit, a peripheral membrane GTPase, to the endoplasmic reticulum membrane | journal = J Cell Biol | volume = 128 | issue = 3 | pages = 273–82 |date=Mar 1995 | pmid = 7844142 | pmc = 2120348 | doi =10.1083/jcb.128.3.273 }}
2. ^{{cite journal | vauthors = Legate KR, Falcone D, Andrews DW | title = Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit | journal = J Biol Chem | volume = 275 | issue = 35 | pages = 27439–46 |date=Oct 2000 | pmid = 10859309 | pmc = | doi = 10.1074/jbc.M003215200 }}
3. ^1 {{cite web | title = Entrez Gene: SRPRB signal recognition particle receptor, B subunit| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=58477| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Bacher G, Pool M, Dobberstein B |title=The Ribosome Regulates the Gtpase of the β-Subunit of the Signal Recognition Particle Receptor |journal=J. Cell Biol. |volume=146 |issue= 4 |pages= 723–30 |year= 1999 |pmid= 10459008 |doi=10.1083/jcb.146.4.723 | pmc=2156146 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Yan W, Wang WL, Zhu F, etal |title=Isolation of a novel member of small G protein superfamily and its expression in colon cancer |journal=World J. Gastroenterol. |volume=9 |issue= 8 |pages= 1719–24 |year= 2003 |pmid= 12918107 |pmc=4611530 |doi= 10.3748/wjg.v9.i8.1719}}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Bouwmeester T, Bauch A, Ruffner H, etal |title=A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway |journal=Nat. Cell Biol. |volume=6 |issue= 2 |pages= 97–105 |year= 2004 |pmid= 14743216 |doi= 10.1038/ncb1086 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
- {{cite journal |vauthors=Li Q, Yan W, Cheng S, etal |title=Introduction of G1 phase arrest in Human Hepatocellular carcinoma cells (HHCC) by APMCF1 gene transfection through the down-regulation of TIMP3 and up-regulation of the CDK inhibitors p21 |journal=Mol. Biol. Rep. |volume=33 |issue= 4 |pages= 257–63 |year= 2007 |pmid= 17080297 |doi= 10.1007/s11033-006-9007-9 }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
{{refend}}{{PDB Gallery|geneid=58477}}{{gene-3-stub}} |