| 词条 | Stephen J. Benkovic |
| 释义 |
| name = Stephen James Benkovic | image = | image_size = | alt = | caption = | birth_date = {{Birth date and age|1938|4|20}} | birth_place = Orange, New Jersey | death_date = | death_place = | residence = | citizenship = | nationality = | fields = mechanistic enzymology, biochemistry | workplaces = Penn State University | alma_mater = Lehigh University, Cornell University, University of California, Santa Barbara | doctoral_advisor = | academic_advisors = Thomas C. Bruice | doctoral_students = | notable_students = | known_for = | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = National Medal of Science (2010) NAS Award in Chemical Sciences (2011) | signature = | signature_alt = | footnotes = | spouse = }}Stephen James Benkovic (born April 20, 1938) is an American chemist. He is Evan Pugh Professor and Eberly Chair in Chemistry at Penn State University.[1] His research has focused on mechanistic enzymology and the discovery of enzyme inhibitors.[2] He was elected to the United States National Academy of Sciences in 1985.[3][4] BiographyEarly life and educationBenkovic was born in Orange, New Jersey. He earned his B.S. degree in chemistry and an A.B. degree in English literature from Lehigh University in 1960. He earned his Ph.D in organic chemistry from Cornell University in 1963.[5] CareerBenkovic was a postdoc at University of California, Santa Barbara. There he and his advisor Thomas C. Bruice developed bioorganic textbooks that focused on enzyme catalysis. He joined the chemistry department at Penn State University in 1965. There, he uses the T4 DNA polymerase as a model system to explain the proficiency of enzymes.[5] He also uses the enzyme dihydrofolate reductase and the pathway for de novo purine biosynthesis to gain insights into enzymatic catalysis. Awards and distinctions
References1. ^{{cite web|url=http://research.chem.psu.edu/sjbgroup/|title=Benkovic Lab|publisher= Benkovic Lab|accessdate=29 March 2010}} 2. ^{{cite web|url=http://www.huck.psu.edu/about/news-archive/stephen-benkovic-honored|title=Stephen Benkovic honored|publisher=Huck Institute|accessdate=29 March 2010}} 3. ^1 2 {{cite web|url=http://www.science.psu.edu/news-and-events/2010-news/Benkovic1-2010|title=Stephen Benkovic Receives Hirschmann Award|publisher=The Pennsylvania State University|accessdate=29 March 2010}} 4. ^[https://books.google.com/books?id=tZHWAAAAMAAJ&q=%22Benkovic,+stephen%22+1938&dq=%22Benkovic,+stephen%22+1938&hl=en&sa=X&ei=N-OWUcbXHej3igLk24HwAQ&ved=0CDoQ6AEwAzgK] 5. ^1 {{cite journal|last=Kresge|first=Nicole |author2=Robert D. Simoni |author3=Robert L. Hill |date=29 October 2009|title=Investigations of the Inner Workings of T4 Polymerase: the Work of Stephen J. Benkovic|journal=The Journal of Biological Chemistry|publisher=The American Society for Biochemistry and Molecular Biology, Inc|volume=284|issue=42|pages=e17–318|url=http://www.jbc.org/content/284/42/e17.full.pdf}} 6. ^{{cite web|title=Book of Members, 1780–2010: Chapter B|url=http://www.amacad.org/publications/BookofMembers/ChapterB.pdf|publisher=American Academy of Arts and Sciences|accessdate=June 13, 2011}} 7. ^{{cite web|url=http://www.theaic.org/award_winners/chem_pioneer.html#cpa60s|title=Chemical Pioneer Award|publisher=American Institute of Chemists|accessdate= 30 November 2015}} 8. ^{{cite web|url=http://www.chem.psu.edu/directory/sjb1|title=Stephen J. Benkovic|publisher=Penn State Department of Chemistry|accessdate=9 February 2011}} 9. ^{{cite web|url=http://www.fi.edu/franklinawards/09/bf_lifesci.html|title=2009 Franklin Institute Awards|publisher=The Franklin Institute|accessdate=29 March 2010}} 10. ^{{cite web|title=President Obama awards chemists National Medals of Science & Technology & Innovation|url=http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pageLabel=PP_ARTICLEMAIN&node_id=222&content_id=CNBP_026080&use_sec=true&sec_url_var=region1&__uuid=960d283f-08d2-4f44-a686-515110782e65|date=November 16, 2010|publisher=American Chemical Society|accessdate=8 February 2011}} 11. ^{{cite web|title=National Academy of Sciences: 2011 NAS Award Recipients|url=http://www.nasonline.org/site/PageServer?pagename=AWARDS_2011_recipients|publisher=National Academy of Sciences|accessdate=8 February 2011|deadurl=yes|archiveurl=https://web.archive.org/web/20110604040616/http://www.nasonline.org/site/PageServer?pagename=AWARDS_2011_recipients|archivedate=4 June 2011|df=}} External links
13 : 1938 births|21st-century American chemists|Cornell University alumni|Fellows of the American Academy of Arts and Sciences|Lehigh University alumni|Living people|Members of the United States National Academy of Sciences|Recipients of awards from the United States National Academy of Sciences|National Medal of Science laureates|Pennsylvania State University faculty|People from Orange, New Jersey|Guggenheim Fellows|Members of the American Philosophical Society |
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