Mighty Mouse is a cartoon superhero.

Mighty Mouse may also refer to:

• The New Adventures, featuring the cartoon character
• Mighty Mouse (film), an upcoming film starring the cartoon character
• a footballer in the British comic strip Hot Shot Hamish and Mighty Mouse footballer
• Mighty Mouse (nickname), various people
• Demetrious Johnson (fighter), a former UFC, currently ONE fc, mixed martial artist
• Michael "Mighty Mouse" Russell (born 1978), tennis player
• A genetic variety of house mouse, Mus musculus, with the Myostatin gene knocked out. Also called "mighty mice", a lack of mysostatin increases muscle mass and strength.
• NTT Mighty Mouse, the first mouse with scroll wheel jointly developed by NTT and ETH Zürich in 1985
• ETH Zürich Mighty Mouse, the first mouse with scroll wheel jointly developed by NTT and ETH Zürich in 1985
• Apple Mighty Mouse, the first multi-button computer mouse produced by Apple Inc.
• Mk 4 FFAR Fin-Folding Aerial Rockets, used by the United States Air Force
• A nickname for the Beechcraft Musketeer aircraft

• We Have a Romeo
• We Have Arrived (album)
• We Have Arrived (song)
• We Have Come for Your Children
• We Have Come For Your Parents
• We Have Come for Your Parents
• We Have Explosive
• We have met the enemy and he is us
• We Haven't Turned Around
• We Have Reason to Believe
• We Have Sound
• We have the facts, and we're voting yes
• We Have the Right to Remain Violent
• WEHCO Media
• WEHCO Media, Inc.
• Wehda
• Wehda Club
• Wehdel station
• Wehem Mesut
• WE Henley
• WEHH
• Wehha
• Wehha of East Anglia
• WEHH radio
• WEHI