“Streptomycin 6-kinase”的意思、由来-开放百科全书

词条

Streptomycin 6-kinase

释义

References

{{enzyme
| Name = streptomycin 6-kinase
| EC_number = 2.7.1.72
| CAS_number = 37278-11-8
| IUBMB_EC_number = 2/7/1/72
| GO_code = 0050300
| image =
| width =
| caption =
}}

In enzymology, a streptomycin 6-kinase ({{EC number|2.7.1.72}}) is an enzyme that catalyzes the chemical reaction

ATP + streptomycin ADP + streptomycin 6-phosphate

Thus, the two substrates of this enzyme are ATP and streptomycin, whereas its two products are ADP and streptomycin 6-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:streptomycin 6-phosphotransferase. Other names in common use include streptidine kinase, SM 6-kinase, streptomycin 6-kinase (phosphorylating), streptidine kinase (phosphorylating), streptomycin 6-O-phosphotransferase, and streptomycin 6-phosphotransferase. This enzyme participates in streptomycin biosynthesis.

References

{{cite journal | vauthors = Walker JB, Skorvaga M | date = 1973 | title = Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives | journal = J. Biol. Chem. | volume = 248 | pages = 2435–40 | pmid = 4121456 | issue = 7 }}
{{cite journal | vauthors = Walker JB, Walker MS | date = 1967 | title = Streptomycin biosynthesis. Enzymatic synthesis of O-phosphorylstreptidine from streptidine and adenosinetriphosphate | journal = Biochim. Biophys. Acta | volume = 148 | pages = 335–41 | pmid = 6075410 | issue = 2 | doi=10.1016/0304-4165(67)90128-6}}

2 : EC 2.7.1|Enzymes of unknown structure

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