| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Syntaxin-5 is a protein that in humans is encoded by the STX5 gene.[1][2][3] Interactions STX5 has been shown to interact with: {{div col|colwidth=20em}}- BET1L,[4][4]
- GOSR1,[5][6][7][8]
- GOSR2,[5][6][7]
- NAPA,[9][10] and
- USO1.[5][11]
{{Div col end}} References 1. ^{{cite journal | vauthors = Ravichandran V, Roche PA | title = Cloning and identification of human syntaxin 5 as a synaptobrevin/VAMP binding protein | journal = Journal of Molecular Neuroscience | volume = 8 | issue = 2 | pages = 159–61 | date = Apr 1997 | pmid = 9188044 | pmc = | doi = 10.1007/BF02736780 }}
2. ^{{cite journal | vauthors = Parlati F, Varlamov O, Paz K, McNew JA, Hurtado D, Söllner TH, Rothman JE | title = Distinct SNARE complexes mediating membrane fusion in Golgi transport based on combinatorial specificity | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 99 | issue = 8 | pages = 5424–9 | date = Apr 2002 | pmid = 11959998 | pmc = 122785 | doi = 10.1073/pnas.082100899 }}
3. ^{{cite web | title = Entrez Gene: STX5 syntaxin 5| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6811| accessdate = }}
4. ^{{cite journal | vauthors = Xu Y, Martin S, James DE, Hong W | title = GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus | journal = Molecular Biology of the Cell | volume = 13 | issue = 10 | pages = 3493–507 | date = Oct 2002 | pmid = 12388752 | pmc = 129961 | doi = 10.1091/mbc.E02-01-0004 }}
5. ^1 2 3 {{cite journal | vauthors = Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G | title = Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115 | journal = The Journal of Cell Biology | volume = 157 | issue = 1 | pages = 45–62 | date = Apr 2002 | pmid = 11927603 | pmc = 2173270 | doi = 10.1083/jcb.200112127 }}
6. ^1 {{cite journal | vauthors = Hay JC, Chao DS, Kuo CS, Scheller RH | title = Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells | journal = Cell | volume = 89 | issue = 1 | pages = 149–58 | date = Apr 1997 | pmid = 9094723 | doi = 10.1016/s0092-8674(00)80191-9}}
7. ^1 {{cite journal | vauthors = Hay JC, Klumperman J, Oorschot V, Steegmaier M, Kuo CS, Scheller RH | title = Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs | journal = The Journal of Cell Biology | volume = 141 | issue = 7 | pages = 1489–502 | date = Jun 1998 | pmid = 9647643 | pmc = 2133002 | doi = 10.1083/jcb.141.7.1489}}
8. ^{{cite journal | vauthors = Subramaniam VN, Loh E, Hong W | title = N-Ethylmaleimide-sensitive factor (NSF) and alpha-soluble NSF attachment proteins (SNAP) mediate dissociation of GS28-syntaxin 5 Golgi SNAP receptors (SNARE) complex | journal = The Journal of Biological Chemistry | volume = 272 | issue = 41 | pages = 25441–4 | date = Oct 1997 | pmid = 9325254 | doi = 10.1074/jbc.272.41.25441}}
9. ^{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
10. ^{{cite journal | vauthors = Rabouille C, Kondo H, Newman R, Hui N, Freemont P, Warren G | title = Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro | journal = Cell | volume = 92 | issue = 5 | pages = 603–10 | date = Mar 1998 | pmid = 9506515 | doi = 10.1016/s0092-8674(00)81128-9}}
11. ^{{cite journal | vauthors = Allan BB, Moyer BD, Balch WE | title = Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion | journal = Science | volume = 289 | issue = 5478 | pages = 444–8 | date = Jul 2000 | pmid = 10903204 | doi = 10.1126/science.289.5478.444}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Nichols BJ, Pelham HR | title = SNAREs and membrane fusion in the Golgi apparatus | journal = Biochimica et Biophysica Acta | volume = 1404 | issue = 1-2 | pages = 9–31 | date = Aug 1998 | pmid = 9714710 | doi = 10.1016/S0167-4889(98)00044-5 }}
- {{cite journal | vauthors = Hay JC, Chao DS, Kuo CS, Scheller RH | title = Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells | journal = Cell | volume = 89 | issue = 1 | pages = 149–58 | date = Apr 1997 | pmid = 9094723 | doi = 10.1016/S0092-8674(00)80191-9 }}
- {{cite journal | vauthors = Paek I, Orci L, Ravazzola M, Erdjument-Bromage H, Amherdt M, Tempst P, Söllner TH, Rothman JE | title = ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi | journal = The Journal of Cell Biology | volume = 137 | issue = 5 | pages = 1017–28 | date = Jun 1997 | pmid = 9166403 | pmc = 2136225 | doi = 10.1083/jcb.137.5.1017 }}
- {{cite journal | vauthors = Rabouille C, Kondo H, Newman R, Hui N, Freemont P, Warren G | title = Syntaxin 5 is a common component of the NSF- and p97-mediated reassembly pathways of Golgi cisternae from mitotic Golgi fragments in vitro | journal = Cell | volume = 92 | issue = 5 | pages = 603–10 | date = Mar 1998 | pmid = 9506515 | doi = 10.1016/S0092-8674(00)81128-9 }}
- {{cite journal | vauthors = Hay JC, Klumperman J, Oorschot V, Steegmaier M, Kuo CS, Scheller RH | title = Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs | journal = The Journal of Cell Biology | volume = 141 | issue = 7 | pages = 1489–502 | date = Jun 1998 | pmid = 9647643 | pmc = 2133002 | doi = 10.1083/jcb.141.7.1489 }}
- {{cite journal | vauthors = Martín-Martín B, Nabokina SM, Lazo PA, Mollinedo F | title = Co-expression of several human syntaxin genes in neutrophils and differentiating HL-60 cells: variant isoforms and detection of syntaxin 1 | journal = Journal of Leukocyte Biology | volume = 65 | issue = 3 | pages = 397–406 | date = Mar 1999 | pmid = 10080545 | doi = }}
- {{cite journal | vauthors = Xu D, Joglekar AP, Williams AL, Hay JC | title = Subunit structure of a mammalian ER/Golgi SNARE complex | journal = The Journal of Biological Chemistry | volume = 275 | issue = 50 | pages = 39631–9 | date = Dec 2000 | pmid = 11035026 | doi = 10.1074/jbc.M007684200 }}
- {{cite journal | vauthors = Shorter J, Beard MB, Seemann J, Dirac-Svejstrup AB, Warren G | title = Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115 | journal = The Journal of Cell Biology | volume = 157 | issue = 1 | pages = 45–62 | date = Apr 2002 | pmid = 11927603 | pmc = 2173270 | doi = 10.1083/jcb.200112127 }}
- {{cite journal | vauthors = Xu Y, Martin S, James DE, Hong W | title = GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus | journal = Molecular Biology of the Cell | volume = 13 | issue = 10 | pages = 3493–507 | date = Oct 2002 | pmid = 12388752 | pmc = 129961 | doi = 10.1091/mbc.E02-01-0004 }}
- {{cite journal | vauthors = Uchiyama K, Jokitalo E, Kano F, Murata M, Zhang X, Canas B, Newman R, Rabouille C, Pappin D, Freemont P, Kondo H | title = VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo | journal = The Journal of Cell Biology | volume = 159 | issue = 5 | pages = 855–66 | date = Dec 2002 | pmid = 12473691 | pmc = 2173386 | doi = 10.1083/jcb.200208112 }}
- {{cite journal | vauthors = Dulubova I, Yamaguchi T, Arac D, Li H, Huryeva I, Min SW, Rizo J, Sudhof TC | title = Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 1 | pages = 32–7 | date = Jan 2003 | pmid = 12506202 | pmc = 140874 | doi = 10.1073/pnas.232701299 }}
- {{cite journal | vauthors = Williams AL, Ehm S, Jacobson NC, Xu D, Hay JC | title = rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility | journal = Molecular Biology of the Cell | volume = 15 | issue = 1 | pages = 162–75 | date = Jan 2004 | pmid = 14565970 | pmc = 307537 | doi = 10.1091/mbc.E03-07-0535 }}
- {{cite journal | vauthors = Hirose H, Arasaki K, Dohmae N, Takio K, Hatsuzawa K, Nagahama M, Tani K, Yamamoto A, Tohyama M, Tagaya M | title = Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi | journal = The EMBO Journal | volume = 23 | issue = 6 | pages = 1267–78 | date = Mar 2004 | pmid = 15029241 | pmc = 381410 | doi = 10.1038/sj.emboj.7600135 }}
- {{cite journal | vauthors = Suga K, Tomiyama T, Mori H, Akagawa K | title = Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production | journal = The Biochemical Journal | volume = 381 | issue = Pt 3 | pages = 619–28 | date = Aug 2004 | pmid = 15109302 | pmc = 1133870 | doi = 10.1042/BJ20040618 }}
- {{cite journal | vauthors = Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W | title = Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network | journal = Molecular Biology of the Cell | volume = 15 | issue = 9 | pages = 4011–22 | date = Sep 2004 | pmid = 15215310 | pmc = 515336 | doi = 10.1091/mbc.E03-12-0876 }}
{{refend}}{{Vesicular transport proteins}}{{gene-11-stub}} |