| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}Sulfotransferase 1A2 is an enzyme that in humans is encoded by the SULT1A2 gene.[1][2][3]Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Two alternatively spliced variants that encode the same protein have been described.[3] References1. ^{{cite journal | vauthors = Her C, Raftogianis R, Weinshilboum RM | title = Human phenol sulfotransferase STP2 gene: molecular cloning, structural characterization, and chromosomal localization | journal = Genomics | volume = 33 | issue = 3 | pages = 409–20 |date=Sep 1996 | pmid = 8661000 | pmc = | doi = 10.1006/geno.1996.0216 }}
2. ^{{cite journal | vauthors = Dooley TP, Huang Z | title = Genomic organization and DNA sequences of two human phenol sulfotransferase genes (STP1 and STP2) on the short arm of chromosome 16 | journal = Biochem Biophys Res Commun | volume = 228 | issue = 1 | pages = 134–40 |date=Dec 1996 | pmid = 8912648 | pmc = | doi = 10.1006/bbrc.1996.1628 }}
3. ^1 {{cite web | title = Entrez Gene: SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6799| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Weinshilboum RM, Otterness DM, Aksoy IA, etal |title=Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. |journal=FASEB J. |volume=11 |issue= 1 |pages= 3–14 |year= 1997 |pmid= 9034160 |doi= 10.1096/fasebj.11.1.9034160}}
- {{cite journal |vauthors=Windmill KF, Christiansen A, Teusner JT, etal |title=Localisation of aryl sulfotransferase expression in human tissues using hybridisation histochemistry and immunohistochemistry. |journal=Chem. Biol. Interact. |volume=109 |issue= 1–3 |pages= 341–6 |year= 1998 |pmid= 9566757 |doi=10.1016/S0009-2797(97)00144-0 }}
- {{cite journal |vauthors=Glatt H, Engelke CE, Pabel U, etal |title=Sulfotransferases: genetics and role in toxicology |journal=Toxicol. Lett. |volume=112-113 |issue= |pages= 341–8 |year= 2000 |pmid= 10720750 |doi=10.1016/S0378-4274(99)00214-3 }}
- {{cite journal | author=Glatt H |title=Sulfotransferases in the bioactivation of xenobiotics |journal=Chem. Biol. Interact. |volume=129 |issue= 1–2 |pages= 141–70 |year= 2001 |pmid= 11154739 |doi=10.1016/S0009-2797(00)00202-7 }}
- {{cite journal |vauthors=Glatt H, Boeing H, Engelke CE, etal |title=Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects |journal=Mutat. Res. |volume=482 |issue= 1–2 |pages= 27–40 |year= 2001 |pmid= 11535246 |doi= 10.1016/S0027-5107(01)00207-X}}
- {{cite journal |vauthors=Ozawa S, Nagata K, Shimada M, etal |title=Primary structures and properties of two related forms of aryl sulfotransferases in human liver |journal=Pharmacogenetics |volume=5 Spec No |issue= |pages= S135–40 |year= 1995 |pmid= 7581483 |doi=10.1097/00008571-199512001-00015 }}
- {{cite journal |vauthors=Yamazoe Y, Ozawa S, Nagata K, etal |title=Characterization and expression of hepatic sulfotransferase involved in the metabolism of N-substituted aryl compounds |journal=Environ. Health Perspect. |volume=102 Suppl 6 |issue= |pages= 99–103 |year= 1995 |pmid= 7889867 |doi= 10.1289/ehp.94102s699| pmc=1566861 }}
- {{cite journal | vauthors=Yamazoe Y, Nagata K, Ozawa S, Kato R |title=Structural similarity and diversity of sulfotransferases |journal=Chem. Biol. Interact. |volume=92 |issue= 1–3 |pages= 107–17 |year= 1994 |pmid= 8033246 |doi=10.1016/0009-2797(94)90057-4 }}
- {{cite journal | vauthors=Zhu X, Veronese ME, Iocco P, McManus ME |title=cDNA cloning and expression of a new form of human aryl sulfotransferase |journal=Int. J. Biochem. Cell Biol. |volume=28 |issue= 5 |pages= 565–71 |year= 1996 |pmid= 8697101 |doi=10.1016/1357-2725(95)00164-6 }}
- {{cite journal | vauthors=Gaedigk A, Beatty BG, Grant DM |title=Cloning, structural organization, and chromosomal mapping of the human phenol sulfotransferase STP2 gene |journal=Genomics |volume=40 |issue= 2 |pages= 242–6 |year= 1997 |pmid= 9119390 |doi= 10.1006/geno.1996.4575 }}
- {{cite journal | vauthors=Harris RM, Waring RH, Kirk CJ, Hughes PJ |title=Sulfation of "estrogenic" alkylphenols and 17beta-estradiol by human platelet phenol sulfotransferases |journal=J. Biol. Chem. |volume=275 |issue= 1 |pages= 159–66 |year= 2000 |pmid= 10617600 |doi=10.1074/jbc.275.1.159 }}
- {{cite journal | vauthors=Engelke CE, Meinl W, Boeing H, Glatt H |title=Association between functional genetic polymorphisms of human sulfotransferases 1A1 and 1A2 |journal=Pharmacogenetics |volume=10 |issue= 2 |pages= 163–9 |year= 2000 |pmid= 10762004 |doi=10.1097/00008571-200003000-00008 }}
- {{cite journal |vauthors=Carlini EJ, Raftogianis RB, Wood TC, etal |title=Sulfation pharmacogenetics: SULT1A1 and SULT1A2 allele frequencies in Caucasian, Chinese and African-American subjects |journal=Pharmacogenetics |volume=11 |issue= 1 |pages= 57–68 |year= 2001 |pmid= 11207031 |doi=10.1097/00008571-200102000-00007 }}
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