| 词条 | Superagonist |
| 释义 |
In the field of pharmacology, a superagonist is a type of agonist that is capable of producing a maximal response greater than the endogenous agonist for the target receptor, and thus has an efficacy of more than 100%.[1][2] For example, goserelin is a superagonist of the gonadotropin-releasing hormone receptor. See also
References1. ^{{Cite journal |vauthors=Carlier PR, Chow ES, Barlow RL, Bloomquist JR | title = Discovery of non-zwitterionic GABAA receptor full agonists and a superagonist | journal = Bioorg. Med. Chem. Lett. | volume = 12 | issue = 15 | pages = 1985–8 |date=August 2002 | pmid = 12113824 | doi = 10.1016/S0960-894X(02)00299-8| url = }} {{Pharmacology}}{{Pharmacology-stub}}2. ^{{Cite journal |vauthors=Tan CM, Wilson MH, MacMillan LB, Kobilka BK, Limbird LE | title = Heterozygous α2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 19 | pages = 12471–6 |date=September 2002 | pmid = 12205290 | pmc = 129469 | doi = 10.1073/pnas.122368499 | url = }} 1 : Receptor agonists |
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