| 释义 |
- References
- Further reading
{{Infobox_gene}}Syncytin-2 also known as endogenous retrovirus group FRD member 1 is a protein that in humans is encoded by the ERVFRD-1 gene.[1] This protein plays a key role in the implantation of human embryos in the womb.[2] References 1. ^{{cite web | title = Entrez Gene: HERV-FRD HERV-FRD provirus ancestral Env polyprotein| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=405754| accessdate = }}
2. ^{{cite journal |vauthors=Vargas A, Moreau J, Landry S, LeBellego F, Toufaily C, Rassart E, Lafond J, Barbeau B |title=Syncytin-2 plays an important role in the fusion of human trophoblast cells |journal=Journal of Molecular Biology |volume=392 |issue=2 |pages=301–18 |year=2009 |pmid=19616006 |doi=10.1016/j.jmb.2009.07.025 |url=}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = de Parseval N, Lazar V, Casella JF, Benit L, Heidmann T | title = Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins | journal = Journal of Virology | volume = 77 | issue = 19 | pages = 10414–22 | date = October 2003 | pmid = 12970426 | pmc = 228468 | doi = 10.1128/JVI.77.19.10414-10422.2003 }}
- {{cite journal | vauthors = Blaise S, de Parseval N, Bénit L, Heidmann T | title = Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 22 | pages = 13013–8 | date = October 2003 | pmid = 14557543 | pmc = 240736 | doi = 10.1073/pnas.2132646100 }}
- {{cite journal | vauthors = Blaise S, Ruggieri A, Dewannieux M, Cosset FL, Heidmann T | title = Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians | journal = Journal of Virology | volume = 78 | issue = 2 | pages = 1050–4 | date = January 2004 | pmid = 14694139 | pmc = 368808 | doi = 10.1128/JVI.78.2.1050-1054.2004 }}
- {{cite journal | vauthors = Renard M, Varela PF, Letzelter C, Duquerroy S, Rey FA, Heidmann T | title = Crystal structure of a pivotal domain of human syncytin-2, a 40 million years old endogenous retrovirus fusogenic envelope gene captured by primates | journal = Journal of Molecular Biology | volume = 352 | issue = 5 | pages = 1029–34 | date = October 2005 | pmid = 16140326 | doi = 10.1016/j.jmb.2005.07.058 }}
- {{cite journal | vauthors = Malassiné A, Blaise S, Handschuh K, Lalucque H, Dupressoir A, Evain-Brion D, Heidmann T | title = Expression of the fusogenic HERV-FRD Env glycoprotein (syncytin 2) in human placenta is restricted to villous cytotrophoblastic cells | journal = Placenta | volume = 28 | issue = 2-3 | pages = 185–91 | year = 2007 | pmid = 16714059 | doi = 10.1016/j.placenta.2006.03.001 | url = http://www.hal.inserm.fr/inserm-00000051 }}
{{refend}}{{PDB Gallery|geneid=405754}}{{protein-stub}} 1 : Endogenous retroviruses |