“TAF8”的意思、由来-开放百科全书

词条

TAF8

释义

References
Further reading

{{Infobox_gene}}Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.^[1]{{PBB_Summary
| section_title =
| summary_text = This gene encodes one of several TATA-binding protein (TBP)-associated factors (TAFs), which are integral subunits of the general transcription factor complex TFIID. TFIID recognizes the core promoter of many genes and nucleates the assembly of a transcription preinitiation complex containing RNA polymerase II and other initiation factors. The protein encoded by this gene contains an H4-like histone fold domain, and interacts with several subunits of TFIID including TBP and the histone-fold protein TAF10. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.^[1]
}}

References

1. ^¹{{cite web | title = Entrez Gene: TBN taube nuss homolog (mouse)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=129685| accessdate = }}

{{cite journal |vauthors=Zhou Q, Sharp PA |title=Novel mechanism and factor for regulation by HIV-1 Tat |journal=EMBO J. |volume=14 |issue= 2 |pages= 321–8 |year= 1995 |pmid= 7835343 |doi= 10.1002/j.1460-2075.1995.tb07006.x| pmc=398086 }}
{{cite journal |vauthors=Parada CA, Yoon JB, Roeder RG |title=A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro |journal=J. Biol. Chem. |volume=270 |issue= 5 |pages= 2274–83 |year= 1995 |pmid= 7836461 |doi=10.1074/jbc.270.5.2274 }}
{{cite journal |vauthors=Ou SH, Garcia-Martínez LF, Paulssen EJ, Gaynor RB |title=Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function |journal=J. Virol. |volume=68 |issue= 11 |pages= 7188–99 |year= 1994 |pmid= 7933101 |doi= | pmc=237158 }}
{{cite journal | author=Kashanchi F |title=Direct interaction of human TFIID with the HIV-1 transactivator tat |journal=Nature |volume=367 |issue= 6460 |pages= 295–9 |year= 1994 |pmid= 8121496 |doi= 10.1038/367295a0 |name-list-format=vanc| author2=Piras G | author3=Radonovich MF | display-authors=3 | last4=Duvall | first4=Janet F. | last5=Fattaey | first5=Ali | last6=Chiang | first6=Cheng-Ming | last7=Roeder | first7=Robert G. | last8=Brady | first8=John N. }}
{{cite journal | author=Wang Z |title=Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro |journal=J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. |volume=12 |issue= 2 |pages= 128–38 |year= 1996 |pmid= 8680883 |doi=10.1097/00042560-199606010-00005 |name-list-format=vanc| author2=Morris GF | author3=Rice AP | display-authors=3 | last4=Xiong | first4=W | last5=Morris | first5=CB }}
{{cite journal |vauthors=Pendergrast PS, Morrison D, Tansey WP, Hernandez N |title=Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly |journal=J. Virol. |volume=70 |issue= 8 |pages= 5025–34 |year= 1996 |pmid= 8764009 |doi= | pmc=190456 }}
{{cite journal | author=Kashanchi F |title=Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex |journal=J. Virol. |volume=70 |issue= 8 |pages= 5503–10 |year= 1996 |pmid= 8764062 |doi= | pmc=190508 |name-list-format=vanc| author2=Khleif SN | author3=Duvall JF | display-authors=3 | last4=Sadaie | first4=MR | last5=Radonovich | first5=MF | last6=Cho | first6=M | last7=Martin | first7=MA | last8=Chen | first8=SY | last9=Weinmann | first9=R }}
{{cite journal |vauthors=Zhou Q, Sharp PA |title=Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat |journal=Science |volume=274 |issue= 5287 |pages= 605–10 |year= 1996 |pmid= 8849451 |doi=10.1126/science.274.5287.605 }}
{{cite journal |vauthors=García-Martínez LF, Ivanov D, Gaynor RB |title=Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes |journal=J. Biol. Chem. |volume=272 |issue= 11 |pages= 6951–8 |year= 1997 |pmid= 9054383 |doi=10.1074/jbc.272.11.6951 }}
{{cite journal | author=Purrello M |title=Genomics and transcription analysis of human TFIID |journal=Oncogene |volume=16 |issue= 12 |pages= 1633–8 |year= 1998 |pmid= 9569032 |doi= 10.1038/sj.onc.1201673 |name-list-format=vanc| author2=Di Pietro C | author3=Viola A | display-authors=3 | last4=Rapisarda | first4=Antonella | last5=Stevens | first5=Sean | last6=Guermah | first6=Mohamed | last7=Tao | first7=Yong | last8=Bonaiuto | first8=Corrada | last9=Arcidiacono | first9=Antonio }}
{{cite journal |vauthors=Guermah M, Tao Y, Roeder RG |title=Positive and Negative TAFII Functions That Suggest a Dynamic TFIID Structure and Elicit Synergy with TRAPs in Activator-Induced Transcription |journal=Mol. Cell. Biol. |volume=21 |issue= 20 |pages= 6882–94 |year= 2001 |pmid= 11564872 |doi= 10.1128/MCB.21.20.6882-6894.2001 | pmc=99865 }}
{{cite journal | author=Tora L |title=A unified nomenclature for TATA box binding protein (TBP)-associated factors (TAFs) involved in RNA polymerase II transcription |journal=Genes Dev. |volume=16 |issue= 6 |pages= 673–5 |year= 2002 |pmid= 11963920 |doi=10.1101/gad.976402 }}
{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
{{cite journal |vauthors=Guermah M, Ge K, Chiang CM, Roeder RG |title=The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis |journal=Mol. Cell |volume=12 |issue= 4 |pages= 991–1001 |year= 2003 |pmid= 14580349 |doi=10.1016/S1097-2765(03)00396-4 }}
{{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
{{cite journal | author=Soutoglou E |title=The Nuclear Import of TAF10 Is Regulated by One of Its Three Histone Fold Domain-Containing Interaction Partners |journal=Mol. Cell. Biol. |volume=25 |issue= 10 |pages= 4092–104 |year= 2005 |pmid= 15870280 |doi= 10.1128/MCB.25.10.4092-4104.2005 | pmc=1087738 |name-list-format=vanc| author2=Demény MA | author3=Scheer E | display-authors=3 | last4=Fienga | first4=G. | last5=Sassone-Corsi | first5=P. | last6=Tora | first6=L. }}

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。

References

Further reading