| 词条 | Taniplon |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451563956 | IUPAC_name = 3-(5-methoxy-6,7,8,9-tetrahydroimidazo[1,2-a]quinazolin-2-yl)-5-methyl-1,2,4-oxadiazole | image = Taniplon_structure.png | width = 200 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 106073-01-2 | ATC_prefix = none | ATC_suffix = | PubChem = 3086516 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = OKS0I0BBLP | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 2343126 | C=14 | H=15 | N=5 | O=2 | molecular_weight = 285.301 g/mol | smiles = CC1=NC(C2=CN3C(N=C(OC)C4=C3CCCC4)=N2)=NO1 | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C14H15N5O2/c1-8-15-12(18-21-8)10-7-19-11-6-4-3-5-9(11)13(20-2)17-14(19)16-10/h7H,3-6H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = OYKONKGGKFFMDV-UHFFFAOYSA-N }} Taniplon is a nonbenzodiazepine anxiolytic drug from the imidazoquinazoline family of drugs. Taniplon binds strongly to benzodiazepine sites on the GABAA receptor and has similar anxiolytic effects in animals, but with less sedative or muscle relaxant action.[1] References1. ^{{cite journal |vauthors=Tully WR, Gardner CR, Gillespie RJ, Westwood R |title=2-(oxadiazolyl)- and 2-(thiazolyl)imidazo[1,2-a]pyrimidines as agonists and inverse agonists at benzodiazepine receptors |journal=Journal of Medicinal Chemistry |volume=34 |issue=7 |pages=2060–7 |date=July 1991 |pmid=1648620 |doi= 10.1021/jm00111a021|url=}} {{Anxiolytics}}{{GABAAR PAMs}} 4 : Sedatives|Imidazoquinazolines|Oxadiazoles|GABAA receptor positive allosteric modulators |
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