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词条 TBL1XR1
释义

  1. Interactions

  2. References

  3. Further reading

{{Infobox_gene}}F-box-like/WD repeat-containing protein TBL1XR1 is a protein that in humans is encoded by the TBL1XR1 gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.[4] Mutations in TBL1XR1 have been identified in lymphomas, including MYD88 wild-type Waldenstrom's Macroglobulinemia[5]
}}

Interactions

TBL1XR1 has been shown to interact with Nuclear receptor co-repressor 1.[2][6][7]

References

1. ^{{cite journal |vauthors=Zhang X, Dormady SP, Basch RS | title = Identification of four human cDNAs that are differentially expressed by early hematopoietic progenitors | journal = Exp Hematol | volume = 28 | issue = 11 | pages = 1286–96 |date=Jan 2001 | pmid = 11063877 | pmc = | doi =10.1016/S0301-472X(00)00539-7 }}
2. ^1 {{cite journal |vauthors=Zhang J, Kalkum M, Chait BT, Roeder RG | title = The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2 | journal = Mol Cell | volume = 9 | issue = 3 | pages = 611–23 |date=Apr 2002 | pmid = 11931768 | pmc = | doi =10.1016/S1097-2765(02)00468-9 }}
3. ^{{cite web | title = Entrez Gene: TBL1XR1 transducin (beta)-like 1X-linked receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79718| accessdate = }}
4. ^{{cite web | title = Entrez Gene: TBL1XR1 transducin (beta)-like 1X-linked receptor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79718| accessdate = }}
5. ^Hunter et al, Proc. American Society for Hematology 2017; Abstract 4011
6. ^{{cite journal |last=Yoon |first=Ho-Geun |authorlink= |author2=Chan Doug W |author3=Reynolds Albert B |author4=Qin Jun |author5=Wong Jiemin |date=Sep 2003 |title=N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso |journal=Mol. Cell |volume=12 |issue=3 |pages=723–34 | issn = 1097-2765| pmid = 14527417 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1016/j.molcel.2003.08.008 }}
7. ^{{cite journal |last=Yoon |first=Ho-Geun |authorlink= |author2=Chan Doug W |author3=Huang Zhi-Qing |author4=Li Jiwen |author5=Fondell Joseph D |author6=Qin Jun |author7=Wong Jiemin |date=Mar 2003 |title=Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1 |journal=EMBO J. |volume=22 |issue=6 |pages=1336–46 | issn = 0261-4189| pmid = 12628926 |doi = 10.1093/emboj/cdg120 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=151047 }}

Further reading

{{refbegin | 2}}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
  • {{cite journal |vauthors=Yoon HG, Chan DW, Huang ZQ, etal |title=Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1. |journal=EMBO J. |volume=22 |issue= 6 |pages= 1336–46 |year= 2003 |pmid= 12628926 |doi= 10.1093/emboj/cdg120 | pmc=151047 }}
  • {{cite journal |vauthors=Yoon HG, Chan DW, Reynolds AB, etal |title=N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. |journal=Mol. Cell |volume=12 |issue= 3 |pages= 723–34 |year= 2003 |pmid= 14527417 |doi=10.1016/j.molcel.2003.08.008 }}
  • {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
  • {{cite journal |vauthors=Perissi V, Aggarwal A, Glass CK, etal |title=A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors. |journal=Cell |volume=116 |issue= 4 |pages= 511–26 |year= 2004 |pmid= 14980219 |doi=10.1016/S0092-8674(04)00133-3 }}
  • {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
  • {{cite journal |vauthors=Yoon HG, Choi Y, Cole PA, Wong J |title=Reading and function of a histone code involved in targeting corepressor complexes for repression. |journal=Mol. Cell. Biol. |volume=25 |issue= 1 |pages= 324–35 |year= 2005 |pmid= 15601853 |doi= 10.1128/MCB.25.1.324-335.2005 | pmc=538779 }}
  • {{cite journal |vauthors=Zhang XM, Chang Q, Zeng L, etal |title=TBLR1 regulates the expression of nuclear hormone receptor co-repressors. |journal=BMC Cell Biol. |volume=7|pages= 31 |year= 2006 |pmid= 16893456 |doi= 10.1186/1471-2121-7-31 | pmc=1555579 }}
  • {{cite journal |vauthors=Liu Y, Sun W, Zhang K, etal |title=Identification of genes differentially expressed in human primary lung squamous cell carcinoma. |journal=Lung Cancer |volume=56 |issue= 3 |pages= 307–17 |year= 2007 |pmid= 17316888 |doi= 10.1016/j.lungcan.2007.01.016 }}
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