| 释义 |
- References
- Further reading
{{Underlinked|date=June 2016}}{{Infobox_gene}}Transcription elongation factor A protein-like 1 is a protein that in humans is encoded by the TCEAL1 gene.[1][2][3]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform.[3]
}}References1. ^{{cite journal | vauthors = Yeh CH, Shatkin AJ | title = A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII | journal = Gene | volume = 143 | issue = 2 | pages = 285–7 |date=Jul 1994 | pmid = 8206389 | pmc = | doi =10.1016/0378-1119(94)90112-0 }}
2. ^{{cite journal | vauthors = Yeh CH, Shatkin AJ | title = Down-regulation of Rous sarcoma virus long terminal repeat promoter activity by a HeLa cell basic protein | journal = Proc Natl Acad Sci U S A | volume = 91 | issue = 23 | pages = 11002–6 |date=Dec 1994 | pmid = 7971997 | pmc = 45154 | doi =10.1073/pnas.91.23.11002 }}
3. ^1 {{cite web | title = Entrez Gene: TCEAL1 transcription elongation factor A (SII)-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9338| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Yeh CH, Zong WX, Shatkin AJ |title=The Ser36-Ser37 pair in HeLa nuclear protein p21/SIIR mediates Ser/Thr phosphorylation and is essential for Rous sarcoma virus long terminal repeat repression |journal=J. Biol. Chem. |volume=270 |issue= 43 |pages= 25313–5 |year= 1995 |pmid= 7592688 |doi=10.1074/jbc.270.44.26558 }}
- {{cite journal | vauthors=Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ |title=Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR |journal=Genomics |volume=56 |issue= 2 |pages= 217–20 |year= 1999 |pmid= 10051408 |doi= 10.1006/geno.1998.5705 }}
- {{cite journal |vauthors=van der Kuip H, Carius B, Haque SJ, etal |title=The DNA-binding subunit p140 of replication factor C is upregulated in cycling cells and associates with G1 phase cell cycle regulatory proteins |journal=J. Mol. Med. |volume=77 |issue= 4 |pages= 386–92 |year= 1999 |pmid= 10353443 |doi=10.1007/s001090050365 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Ross MT, Grafham DV, Coffey AJ, etal |title=The DNA sequence of the human X chromosome |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440 | pmc=2665286 }}
- {{cite journal |vauthors=Makino H, Tajiri T, Miyashita M, etal |title=Differential expression of TCEAL1 in esophageal cancers by custom cDNA microarray analysis |journal=Dis. Esophagus |volume=18 |issue= 1 |pages= 37–40 |year= 2005 |pmid= 15773840 |doi= 10.1111/j.1442-2050.2005.00432.x }}
- {{cite journal |vauthors=Oh JH, Yang JO, Hahn Y, etal |title=Transcriptome analysis of human gastric cancer |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942–54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2 }}
- {{cite journal |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein–protein interactions by mass spectrometry |journal=Mol. Syst. Biol. |volume=3 |issue= 1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
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