| 词条 | Temocapril |
| 释义 |
| verifiedrevid = 443436190 | IUPAC_name = 2-[(2S)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid | image = Temocapril.svg | tradename = | Drugs.com = {{drugs.com|international|temocapril}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | dependency_liability = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 111902-57-9 | ATC_prefix = C09 | ATC_suffix = AA14 | ATC_supplemental = | PubChem = 71323 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChEMBL = 2110627 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 18IZ008EU6 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D08566 | ChemSpiderID = 64431 | chemical_formula = | C=23 | H=28 | N=2 | O=5 | S=2 | molecular_weight = 476.608 g/mol | smiles = CCOC(=O)[C@H](CCc1ccccc1)NC2CS[C@@H](CN(C2=O)CC(=O)O)c3cccs3 | StdInChI = 1S/C23H28N2O5S2/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27)/t17-,18?,20-/m0/s1 | StdInChIKey = FIQOFIRCTOWDOW-DXCJPMOASA-N }} Temocapril (also known as temocaprilum [Latin]; brand name Acecol) is an ACE inhibitor. It was not approved for use in the US. It was patented in 1984 and approved for medical use in 1994.[1] References1. ^{{cite book |last1=Fischer |first1=Jnos |last2=Ganellin |first2=C. Robin |title=Analogue-based Drug Discovery |date=2006 |publisher=John Wiley & Sons |isbn=9783527607495 |page=469 |url=https://books.google.ca/books?id=FjKfqkaKkAAC&pg=PA469 |language=en}} {{ACE inhibitors}}{{Angiotensin receptor modulators}}{{cardiovascular-drug-stub}} 11 : ACE inhibitors|Acetic acids|Enantiopure drugs|Ethyl esters|Lactams|Prodrugs|Thiophenes|Butyrates|Nitrogen heterocycles|Sulfur heterocycles|Heterocyclic compounds (1 ring) |
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