“Morbillivirus”的意思、由来-开放百科全书

词条

Morbillivirus

释义

Taxonomy
Structure
Life cycle
References
External links

{{Use dmy dates|date=April 2017}}{{Virusbox
| image = Measles virus.JPG
| image_alt = "Measles morbillivirus" electron micrograph
| image_caption = Measles morbillivirus electron micrograph
| taxon = Morbillivirus
| authority =
| type_species = Measles morbillivirus
| synonyms =
| synonyms_ref =
| subdivision_ranks = Species
| subdivision =

Canine morbillivirus
Cetacean morbillivirus
Feline morbillivirus
Feline morbillivirus 2
Measles morbillivirus
Phocine morbillivirus
Rinderpest morbillivirus
Small ruminant morbillivirus

}}Morbillivirus is a genus of viruses in the order Mononegavirales, in the family Paramyxoviridae. Humans, dogs, cats, cattle, and cetaceans serve as natural hosts. This genus currently included seven species. Diseases in humans associated with viruses classified in this genus include measles: fever, and rash; in animals, they include acute febrile respiratory tract infection.^[1]^[2]

Taxonomy

Genus *Morbillivirus*: species and their viruses^[3]
Genus	Species	Virus (Abbreviation)
Morbillivirus	Canine morbillivirus	Canine distemper virus (CDV)
	Cetacean morbillivirus	Cetacean morbillivirus (CeMV)
	Feline morbillivirus	Feline morbillivirus (FeMV)
	Feline morbillivirus 2	Feline morbillivirus 2 (FeMV 2)
	Measles morbillivirus*	Measles virus (MeV)
	Ovine rinderpest	Peste-des-petits-ruminants virus (PPRV)
	Phocine morbillivirus	Phocine distemper virus (PDV)
	Rinderpest morbillivirus	Rinderpest virus (RPV)

Table legend: "*" denotes type species

Structure

Morbillivirions are enveloped, with spherical geometries. Their diameter is around 150 nm. Genomes are linear, around 15-16 kb in length. The genome codes for eight proteins.^[1]

Genus	Structure	Symmetry	Capsid	Genomic arrangement	Genomic segmentation
Morbillivirus	Spherical	Enveloped	Linear	Monopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by virus attaching to host cell. Replication follows the negative-stranded RNA virus replication model. Negative-stranded RNA virus transcription, using polymerase stuttering, through co-transcriptional RNA editing is the method of transcription. Translation takes place by leaky scanning. The virus exits the host cell by budding.

Humans, dogs, cattle, and cetaceans serve as the natural hosts. Transmission routes are respiratory.^[1]

Genus	Host details	Tissue tropism	Entry details	Release details	Replication site	Assembly site	Transmission
Morbillivirus	Humans, dogs, cats, cetaceans	None	Glycoprotein	Budding	Cytoplasm	Cytoplasm	Aerosols

References

1. ^¹²{{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/86.html|publisher=ExPASy|accessdate=13 August 2015}}
2. ^{{cite web|last1=ICTV|title=Virus Taxonomy: 2014 Release|url=http://ictvonline.org/virusTaxonomy.asp|accessdate=13 August 2015}}
3. ^{{Cite journal|last=Amarasinghe|first=Gaya K.|last2=Bào|first2=Yīmíng|last3=Basler|first3=Christopher F.|last4=Bavari|first4=Sina|last5=Beer|first5=Martin|last6=Bejerman|first6=Nicolás|last7=Blasdell|first7=Kim R.|last8=Bochnowski|first8=Alisa|last9=Briese|first9=Thomas|date=2017-04-07|title=Taxonomy of the order Mononegavirales: update 2017|journal=Archives of Virology|doi=10.1007/s00705-017-3311-7|issn=1432-8798|pmid=28389807}}

External links

Viralzone: Morbillivirus
ICTV
Virus Pathogen Database and Analysis Resource (ViPR): Paramyxoviridae

3 : Morbilliviruses|Paramyxoviridae|Mononegavirales

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