| 释义 |
- References
- Further reading
{{Infobox_gene}}Tumor necrosis factor (ligand) superfamily, member 12-member 13, also known as TNFSF12-TNFSF13, is a human gene.[1]{{PBB_Summary
| section_title =
| summary_text = This gene belongs to the tumor necrosis factor superfamily (TNFSF). It encodes a hybrid protein composed of the cytoplasmic and transmembrane domains of the family member 12 fused to the C-terminal domain of the family member 13. The hybrid protein is membrane anchored and presents the receptor-binding domain of the family member 13 at the cell surface. It stimulates cycling in T-lymphoma and B-lymphoma cell lines. The mRNA transcript is expressed and translated in primary T cells and monocytes.[1]
}}References1. ^1 {{cite web | title = Entrez Gene: TNFSF12-TNFSF13 tumor necrosis factor (ligand) superfamily, member 12-member 13| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=407977| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | author=Hahne M |title=APRIL, a New Ligand of the Tumor Necrosis Factor Family, Stimulates Tumor Cell Growth |journal=J. Exp. Med. |volume=188 |issue= 6 |pages= 1185–90 |year= 1998 |pmid= 9743536 |doi=10.1084/jem.188.6.1185 | pmc=2212534 |name-list-format=vanc| author2=Kataoka T | author3=Schröter M | display-authors=3 | last4=Hofmann | first4=K | last5=Irmler | first5=M | last6=Bodmer | first6=JL | last7=Schneider | first7=P | last8=Bornand | first8=T | last9=Holler | first9=N }}
- {{cite journal | author=Kelly K |title=APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death |journal=Cancer Res. |volume=60 |issue= 4 |pages= 1021–7 |year= 2000 |pmid= 10706119 |doi= |name-list-format=vanc| author2=Manos E | author3=Jensen G | display-authors=3 | last4=Nadauld | first4=L | last5=Jones | first5=DA }}
- {{cite journal | author=Wu Y |title=Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS |journal=J. Biol. Chem. |volume=275 |issue= 45 |pages= 35478–85 |year= 2001 |pmid= 10956646 |doi= 10.1074/jbc.M005224200 |name-list-format=vanc| author2=Bressette D | author3=Carrell JA | display-authors=3 | last4=Kaufman | first4=T | last5=Feng | first5=P | last6=Taylor | first6=K | last7=Gan | first7=Y | last8=Cho | first8=YH | last9=Garcia | first9=AD }}
- {{cite journal | author=Yu G |title=APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity |journal=Nat. Immunol. |volume=1 |issue= 3 |pages= 252–6 |year= 2001 |pmid= 10973284 |doi= 10.1038/79802 |name-list-format=vanc| author2=Boone T | author3=Delaney J | display-authors=3 | last4=Hawkins | first4=Nessa | last5=Kelley | first5=Michael | last6=Ramakrishnan | first6=Meena | last7=McCabe | first7=Susan | last8=Qiu | first8=Wan-Rong | last9=Kornuc | first9=Masayo }}
- {{cite journal |vauthors=López-Fraga M, Fernández R, Albar JP, Hahne M |title=Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase |journal=EMBO Rep. |volume=2 |issue= 10 |pages= 945–51 |year= 2002 |pmid= 11571266 |doi= 10.1093/embo-reports/kve198 | pmc=1084076 }}
- {{cite journal | author=Roschke V |title=BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases |journal=J. Immunol. |volume=169 |issue= 8 |pages= 4314–21 |year= 2002 |pmid= 12370363 |doi= 10.4049/jimmunol.169.8.4314|name-list-format=vanc| author2=Sosnovtseva S | author3=Ward CD | display-authors=3 | last4=Hong | first4=JS | last5=Smith | first5=R | last6=Albert | first6=V | last7=Stohl | first7=W | last8=Baker | first8=KP | last9=Ullrich | first9=S }}
- {{cite journal | author=Pradet-Balade B |title=An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK–APRIL fusion protein |journal=EMBO J. |volume=21 |issue= 21 |pages= 5711–20 |year= 2002 |pmid= 12411489 |doi=10.1093/emboj/cdf565 | pmc=131062 |name-list-format=vanc| author2=Medema JP | author3=López-Fraga M | display-authors=3 | last4=Lozano | first4=JC | last5=Kolfschoten | first5=GM | last6=Picard | first6=A | last7=Martínez-a | first7=C | last8=Garcia-Sanz | first8=JA | last9=Hahne | first9=M }}
- {{cite journal | author=Hendriks J |title=Heparan sulfate proteoglycan binding promotes APRIL-induced tumor cell proliferation |journal=Cell Death Differ. |volume=12 |issue= 6 |pages= 637–48 |year= 2005 |pmid= 15846369 |doi= 10.1038/sj.cdd.4401647 |name-list-format=vanc| author2=Planelles L | author3=de Jong-Odding J | display-authors=3 | last4=Hardenberg | first4=G | last5=Pals | first5=S T | last6=Hahne | first6=M | last7=Spaargaren | first7=M | last8=Medema | first8=J P }}
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