| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Tankyrase-2 is an enzyme that in humans is encoded by the TNKS2 gene.[1]{{PBB_Summary
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}}InteractionsTNKS2 has been shown to interact with GRB14,[2] TERF1[3][4][5] and Cystinyl aminopeptidase.[4][5][6] References1. ^{{cite web | title = Entrez Gene: TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=80351| accessdate = }}
2. ^{{cite journal |last=Lyons |first=R J |authorlink= |author2=Deane R |author3=Lynch D K |author4=Ye Z S |author5=Sanderson G M |author6=Eyre H J |author7=Sutherland G R |author8=Daly R J |date=May 2001 |title=Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14 |journal=J. Biol. Chem. |volume=276 |issue=20 |pages=17172–80 |publisher= |location = United States| issn = 0021-9258| pmid = 11278563 |doi = 10.1074/jbc.M009756200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
3. ^{{cite journal |doi=10.1128/MCB.22.1.332-342.2002 |last=Cook |first=Brandoch D |authorlink= |author2=Dynek Jasmin N |author3=Chang William |author4=Shostak Grigoriy |author5=Smith Susan |date=January 2002 |title=Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres |journal=Mol. Cell. Biol. |volume=22 |issue=1 |pages=332–42 |publisher= |location = United States| issn = 0270-7306| pmid = 11739745 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=134233 }}
4. ^1 {{cite journal |last=Chi |first=N W |authorlink= |author2=Lodish H F |date=Dec 2000 |title=Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles |journal=J. Biol. Chem. |volume=275 |issue=49 |pages=38437–44 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10988299 |doi = 10.1074/jbc.M007635200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
5. ^1 {{cite journal |doi=10.1042/0264-6021:3610451 |last=Sbodio |first=Juan I |authorlink= |author2=Lodish Harvey F |author3=Chi Nai-Wen |date=February 2002 |title=Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase) |journal=Biochem. J. |volume=361 |issue=Pt 3 |pages=451–9 |publisher= |location = England| issn = 0264-6021| pmid = 11802774 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1222327 }}
6. ^{{cite journal |last=Sbodio |first=Juan I |authorlink= |author2=Chi Nai-Wen |date=August 2002 |title=Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner |journal=J. Biol. Chem. |volume=277 |issue=35 |pages=31887–92 |publisher= |location = United States| issn = 0021-9258| pmid = 12080061 |doi = 10.1074/jbc.M203916200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
Further reading{{Refbegin | 2}}- {{cite journal |vauthors=Monz D, Munnia A, Comtesse N, etal |title=Novel tankyrase-related gene detected with meningioma-specific sera. |journal=Clin. Cancer Res. |volume=7 |issue= 1 |pages= 113–9 |year= 2001 |pmid= 11205898 |doi= }}
- {{cite journal |vauthors=Lyons RJ, Deane R, Lynch DK, etal |title=Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14. |journal=J. Biol. Chem. |volume=276 |issue= 20 |pages= 17172–80 |year= 2001 |pmid= 11278563 |doi= 10.1074/jbc.M009756200 }}
- {{cite journal |vauthors=Kuimov AN, Kuprash DV, Petrov VN, etal |title=Cloning and characterization of TNKL, a member of tankyrase gene family. |journal=Genes Immun. |volume=2 |issue= 1 |pages= 52–5 |year= 2001 |pmid= 11294570 |doi= 10.1038/sj.gene.6363722 }}
- {{cite journal |vauthors=Kaminker PG, Kim SH, Taylor RD, etal |title=TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression. |journal=J. Biol. Chem. |volume=276 |issue= 38 |pages= 35891–9 |year= 2001 |pmid= 11454873 |doi= 10.1074/jbc.M105968200 }}
- {{cite journal |vauthors=Cook BD, Dynek JN, Chang W, etal |title=Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. |journal=Mol. Cell. Biol. |volume=22 |issue= 1 |pages= 332–42 |year= 2002 |pmid= 11739745 |doi=10.1128/MCB.22.1.332-342.2002 | pmc=134233 }}
- {{cite journal |vauthors=Sbodio JI, Lodish HF, Chi NW |title=Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase). |journal=Biochem. J. |volume=361 |issue= Pt 3 |pages= 451–9 |year= 2002 |pmid= 11802774 |doi=10.1042/0264-6021:3610451 | pmc=1222327 }}
- {{cite journal |vauthors=Seimiya H, Smith S |title=The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). |journal=J. Biol. Chem. |volume=277 |issue= 16 |pages= 14116–26 |year= 2002 |pmid= 11854288 |doi= 10.1074/jbc.M112266200 }}
- {{cite journal |vauthors=Sbodio JI, Chi NW |title=Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31887–92 |year= 2002 |pmid= 12080061 |doi= 10.1074/jbc.M203916200 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Deloukas P, Earthrowl ME, Grafham DV, etal |title=The DNA sequence and comparative analysis of human chromosome 10. |journal=Nature |volume=429 |issue= 6990 |pages= 375–81 |year= 2004 |pmid= 15164054 |doi= 10.1038/nature02462 |bibcode=2004Natur.429..375D }}
- {{cite journal |vauthors=Deng Z, Atanasiu C, Zhao K, etal |title=Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1. |journal=J. Virol. |volume=79 |issue= 8 |pages= 4640–50 |year= 2005 |pmid= 15795250 |doi= 10.1128/JVI.79.8.4640-4650.2005 | pmc=1069541 }}
- {{cite journal |vauthors=Sidorova N, Zavalishina L, Kurchashova S, etal |title=Immunohistochemical detection of tankyrase 2 in human breast tumors and normal renal tissue. |journal=Cell Tissue Res. |volume=323 |issue= 1 |pages= 137–45 |year= 2006 |pmid= 16151859 |doi= 10.1007/s00441-005-0053-8 }}
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