词条 | Tolciclate |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 448221674 | IUPAC_name = O-Tricyclo[6.2.1.02,7]undeca-2,4,6-trien-4-yl methyl(3-methylphenyl)carbamothioate | image = Tolciclate.svg | image2 = Tolciclate 3D spacefill.png | width2 = 200 | alt2 = Space-filling model of the tolciclate molecule | tradename = | Drugs.com = {{drugs.com|international|tolciclate}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 50838-36-3 | ATC_prefix = D01 | ATC_suffix = AE19 | PubChem = 5506 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = T3TZ02X2AZ | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D01384 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 5305 | synonyms = O-(1,2,3,4-Tetrahydro-1,4-methanonaphthalen-6-yl) m,N-dimethylthiocarbanilate[1] | C=20 | H=21 | N=1 | O=1 | S=1 | molecular_weight = 323.45 g/mol | smiles = Cc1cccc(c1)N(C)C(=S)Oc2ccc3c(c2)C4CCC3C4 | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C20H21NOS/c1-13-4-3-5-16(10-13)21(2)20(23)22-17-8-9-18-14-6-7-15(11-14)19(18)12-17/h3-5,8-10,12,14-15H,6-7,11H2,1-2H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = CANCCLAKQQHLNK-UHFFFAOYSA-N }}Tolciclate (INN)[1]{{rp|9}} is an antifungal medication.[2][3] See also
References1. ^1 {{cite web|title=International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary names: List 15|url=http://www.who.int/medicines/publications/druginformation/innlists/RL15.pdf|publisher=World Health Organization|accessdate=12 November 2016|date=1975}} {{Antifungals}}{{antiinfective-drug-stub}}{{dermatologic-drug-stub}}2. ^{{ cite journal |author1=Ryder, N. S. |author2=Frank, I. |author3=Dupont, M. C. | title = Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate | journal = Antimicrobial Agents and Chemotherapy | volume = 29 | issue = 5 | pages = 858–860 |date=May 1986 | pmid = 3524433 | pmc = 284167 | doi = 10.1128/aac.29.5.858| url = http://aac.asm.org/cgi/pmidlookup?view=long&pmid=3524433 }} 3. ^{{ cite journal |author1=Bianchi, A. |author2=Monti, G. |author3=de Carneri, I. | title = Tolciclate: further antimycotic studies | journal = Antimicrobial Agents and Chemotherapy | volume = 12 | issue = 3 | pages = 429–430 |date=September 1977 | pmid = 907333 | pmc = 429931 | doi = 10.1128/aac.12.3.429| url = http://aac.asm.org/cgi/pmidlookup?view=long&pmid=907333 }} 3 : Antifungals|Tetralins|Thiocarbamates |
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