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词条 TPK1
释义

  1. References

  2. Further reading

{{Infobox_gene}}Thiamin pyrophosphokinase 1 is an enzyme that in humans is encoded by the TPK1 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[2]
}}

References

1. ^{{cite journal |vauthors=Nosaka K, Onozuka M, Kakazu N, Hibi S, Nishimura H, Nishino H, Abe T | title = Isolation and characterization of a human thiamine pyrophosphokinase cDNA | journal = Biochim Biophys Acta | volume = 1517 | issue = 2 | pages = 293–7 |date=May 2001 | pmid = 11342111 | pmc = | doi = 10.1016/s0167-4781(00)00247-5}}
2. ^{{cite web | title = Entrez Gene: TPK1 thiamin pyrophosphokinase 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27010| accessdate = }}

Further reading

{{refbegin | 2}}
  • {{cite journal | author=Egi Y |title=Identification, purification and reconstitution of thiamin metabolizing enzymes in human red blood cells |journal=Biochim. Biophys. Acta |volume=1160 |issue= 2 |pages= 171–8 |year= 1992 |pmid= 1332781 |doi=10.1016/0167-4838(92)90004-W |name-list-format=vanc| author2=Koyama S | author3=Shioda T | display-authors=3 | last4=Yamada | first4=K | last5=Kawasaki | first5=T }}
  • {{cite journal |vauthors=Bohn H, Winckler W |title=Isolation and characterization of four new placental tissue proteins (PP18, PP19, PP20, PP21) |journal=Arch. Gynecol. |volume=236 |issue= 4 |pages= 235–42 |year= 1985 |pmid= 3896163 |doi=10.1007/BF02133941 }}
  • {{cite journal |vauthors=Iwashima A, Kinugasa A, Nose Y |title=Radiometric assay for thiamine pyrophosphokinase activity in human leukocytes |journal=Acta Vitaminol. Enzymol. |volume=5 |issue= 1 |pages= 41–5 |year= 1983 |pmid= 6303095 |doi= }}
  • {{cite journal |title=Toward a complete human genome sequence |journal=Genome Res. |volume=8 |issue= 11 |pages= 1097–108 |year= 1999 |pmid= 9847074 |doi= 10.1101/gr.8.11.1097 | author1= }}
  • {{cite journal | author=Nosaka K |title=Molecular cloning and expression of a mouse thiamin pyrophosphokinase cDNA |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 34129–33 |year= 1999 |pmid= 10567383 |doi=10.1074/jbc.274.48.34129 |name-list-format=vanc| author2=Onozuka M | author3=Nishino H | display-authors=3 | last4=Nishimura | first4=H | last5=Kawasaki | first5=Y | last6=Ueyama | first6=H }}
  • {{cite journal |vauthors=Zhao R, Gao F, Goldman ID |title=Molecular cloning of human thiamin pyrophosphokinase |journal=Biochim. Biophys. Acta |volume=1517 |issue= 2 |pages= 320–2 |year= 2001 |pmid= 11342117 |doi= 10.1016/s0167-4781(00)00264-5}}
  • {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
  • {{cite journal | author=Scherer SW |title=Human Chromosome 7: DNA Sequence and Biology |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 | pmc=2882961 |name-list-format=vanc| author2=Cheung J | author3=MacDonald JR | display-authors=3 | last4=Osborne | first4=LR | last5=Nakabayashi | first5=K | last6=Herbrick | first6=JA | last7=Carson | first7=AR | last8=Parker-Katiraee | first8=L | last9=Skaug | first9=J }}
  • {{cite journal |vauthors=Onozuka M, Nosaka K |title=Steady-state kinetics and mutational studies of recombinant human thiamin pyrophosphokinase |journal=J. Nutr. Sci. Vitaminol. |volume=49 |issue= 3 |pages= 156–62 |year= 2004 |pmid= 12953792 |doi= 10.3177/jnsv.49.156}}
  • {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
  • {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
  • {{cite journal | author=Bellyei S |title=Cloning, sequencing, structural and molecular biological characterization of placental protein 20 (PP20)/human thiamin pyrophosphokinase (hTPK) |journal=Placenta |volume=26 |issue= 1 |pages= 34–46 |year= 2005 |pmid= 15664409 |doi= 10.1016/j.placenta.2004.03.008 |name-list-format=vanc| author2=Szigeti A | author3=Boronkai A | display-authors=3 | last4=Szabo | first4=Z. | last5=Bene | first5=J. | last6=Janaky | first6=T. | last7=Barna | first7=L. | last8=Sipos | first8=K. | last9=Minik | first9=O. }}
  • {{cite journal | author=Toyoshima M |title=Thiamine-responsive congenital lactic acidosis: clinical and biochemical studies |journal=Pediatr. Neurol. |volume=33 |issue= 2 |pages= 98–104 |year= 2005 |pmid= 16087053 |doi= 10.1016/j.pediatrneurol.2005.02.007 |name-list-format=vanc| author2=Oka A | author3=Egi Y | display-authors=3 | last4=Yamamoto | first4=T | last5=Onozuka | first5=M | last6=Nosaka | first6=K | last7=Naito | first7=E | last8=Yamada | first8=K }}
  • {{cite journal | author=Onozuka M |title=Molecular cloning and analysis of the 5'-flanking region of the human thiamin pyrophosphokinase gene |journal=J. Nutr. Sci. Vitaminol. |volume=51 |issue= 4 |pages= 274–7 |year= 2006 |pmid= 16262001 |doi= 10.3177/jnsv.51.274|name-list-format=vanc| author2=Konno H | author3=Akaji K | display-authors=3 | last4=Nishino | first4=H | last5=Nosaka | first5=K }}
  • {{cite journal | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 |name-list-format=vanc| author2=Wakamatsu A | author3=Suzuki Y | display-authors=3 | last4=Ota | first4=T | last5=Nishikawa | first5=T | last6=Yamashita | first6=R | last7=Yamamoto | first7=J | last8=Sekine | first8=M | last9=Tsuritani | first9=K }}
  • {{cite journal |vauthors=Fradin D, Bougneres P |title=Three common intronic variants in the maternal and fetal thiamine pyrophosphokinase gene (TPK1) are associated with birth weight |journal=Ann. Hum. Genet. |volume=71 |issue= Pt 5 |pages= 578–85 |year= 2007 |pmid= 17295612 |doi= 10.1111/j.1469-1809.2007.00348.x }}
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