| 词条 | Triamcinolone benetonide |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 3-(benzoylamino)-2-methylpropanoate | image = Triamcinolone benetonide.svg | width = | tradename = Alcorten, Benecorten, Tibicorten | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 31002-79-6 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 62963 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 56674 | UNII = | KEGG = | ChEBI = 135852 | ChEMBL = 2105798 | C=35 | H=42 | F=1 | N=1 | O=8 | SMILES = CC(CNC(=O)C1=CC=CC=C1)C(=O)OCC(=O)[C@@]23[C@@H](C[C@@H]4[C@@]2(C[C@@H]([C@]5([C@H]4CCC6=CC(=O)C=C[C@@]65C)F)O)C)OC(O3)(C)C | StdInChI_Ref = | StdInChI = 1S/C35H42FNO8/c1-20(18-37-29(41)21-9-7-6-8-10-21)30(42)43-19-27(40)35-28(44-31(2,3)45-35)16-25-24-12-11-22-15-23(38)13-14-32(22,4)34(24,36)26(39)17-33(25,35)5/h6-10,13-15,20,24-26,28,39H,11-12,16-19H2,1-5H3,(H,37,41)/t20?,24-,25-,26-,28+,32-,33-,34-,35+/m0/s1 | StdInChIKey_Ref = | StdInChIKey = GUYPYYARYIIWJZ-CYEPYHPTSA-N | synonyms = Triamcinolone acetonide benzoyl-β-aminoisobutyrate; TBI; 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-ester with N-benzoyl-2-methyl-β-alanine }}Triamcinolone benetonide (brand names Alcorten, Benecorten, Tibicorten; also known as triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate) or TBI) is a synthetic glucocorticoid corticosteroid.[1][2][3] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA1228|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=1228–}} {{Glucocorticoids and antiglucocorticoids}}{{Glucocorticoid receptor modulators}}{{steroid-stub}}2. ^{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=RA1-PA1657|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=1657–}} 3. ^{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA280|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=280–}} 10 : Acetonides|Alcohols|Benzamides|Corticosteroid esters|Fluoroarenes|Glucocorticoids|Isobutyrates|Phenyl compounds|Pregnanes|Tetraones |
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