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词条 Triamcinolone furetonide
释义

  1. References

{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-Fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-2-oxo-2,4a,4b,5,6,6a,9a,10,10a,10b,11,12-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl 1-benzofuran-2-carboxylate
| image = Triamcinolone furetonide.svg
| width =
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref =
| CAS_number = 4989-94-0
| CAS_supplemental =
| class = Corticosteroid; Glucocorticoid
| ATC_prefix =
| ATC_suffix =
| ATC_supplemental =
| PubChem = 62964
| IUPHAR_ligand =
| DrugBank_Ref =
| DrugBank =
| ChemSpiderID_Ref =
| ChemSpiderID = 56675
| UNII = O49NOC9ROC
| KEGG =
| ChEBI =
| ChEMBL = 2105791
| C=33 | H=35 | F=1 | O=8
| SMILES = C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)COC(=O)C5=CC6=CC=CC=C6O5)CCC7=CC(=O)C=C[C@@]73C)F)O
| StdInChI_Ref =
| StdInChI = 1S/C33H35FO8/c1-29(2)41-27-15-22-21-10-9-19-14-20(35)11-12-30(19,3)32(21,34)25(36)16-31(22,4)33(27,42-29)26(37)17-39-28(38)24-13-18-7-5-6-8-23(18)40-24/h5-8,11-14,21-22,25,27,36H,9-10,15-17H2,1-4H3/t21-,22-,25-,27+,30-,31-,32-,33+/m0/s1
| StdInChIKey_Ref =
| StdInChIKey = OSWKQSQWSQSPQH-GNFRAIDCSA-N
| synonyms = HE-192; Triamcinolone acetonide 21-(2-benzofurancarboxylate); 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-(2-benzofurancarboxylate)
}}Triamcinolone furetonide (developmental code name HE-192; also known as triamcinolone acetonide 21-(2-benzofurancarboxylate)) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3]

References

1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA1228|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=1228–}}
2. ^{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=RA1-PA1657|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=1657–}}
3. ^{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA280|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=280–}}
{{Glucocorticoid receptor modulators}}{{steroid-stub}}

8 : Acetonides|Alcohols|Corticosteroid esters|Fluoroarenes|Glucocorticoids|Pregnanes|Triketones|Abandoned drugs

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