“Triphosphate—protein phosphotransferase”的意思、由来-开放百科全书

词条

Triphosphate—protein phosphotransferase

释义

Classification
Nomenclature
References

{{enzyme
| Name = diphosphate-protein phosphotransferase
| EC_number = 2.7.99.1
| CAS_number = 74092-32-3
| IUBMB_EC_number = 2/7/99/1
| GO_code = 0047321
| image =
| width =
| caption =
}}

In enzymology, a triphosphate-protein phosphotransferase ({{EC number|2.7.99.1}}) is an enzyme that catalyzes the chemical reaction

triphosphate + [microsomal-membrane protein] diphosphate + phospho-[microsomal-membrane protein]

Thus, the two substrates of this enzyme are triphosphate and microsomal-membrane protein, whereas its two products are diphosphate and phospho-[microsomal-membrane protein].

Classification

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups that are not covered by other phosphotransferase families.

Nomenclature

The systematic name of this enzyme class is triphosphate:[microsomal-membrane-protein] phosphotransferase. Other names in common use include diphosphate:microsomal-membrane-protein O-phosphotransferase, (erroneous), DiPPT (erroneous), pyrophosphate:protein phosphotransferase (erroneous), diphosphate-protein phosphotransferase (erroneous), diphosphate:[microsomal-membrane-protein] O-phosphotransferase, and (erroneous).

References

{{cite journal |vauthors=Lam KS, Kasper CB | year = 1980 | title = Pyrophosphate:protein phosphotransferase: a membrane-bound enzyme of endoplasmic reticulum | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 77 | pages = 1927–31 | pmid = 6246514 | doi = 10.1073/pnas.77.4.1927 | issue = 4 | pmc = 348622 }}
{{cite journal | author = Tsutsui K | year = 1986 | title = Tripolyphosphate is an alternative phosphodonor of the selective protein phosphorylation of liver microsomal membrane | journal = J. Biol. Chem. | volume = 261 | pages = 2645–53 | pmid = 3949741 | issue = 6 }}

{{Kinases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{DEFAULTSORT:Triphosphate-protein phosphotransferase}}{{2.7-enzyme-stub}}

2 : EC 2.7.99|Enzymes of unknown structure

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