“Tropic acid”的意思、由来-开放百科全书

词条

Tropic acid

释义

Synthesis
References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 428732081
| ImageFile=tropic acid.png
| ImageSize=200px
| IUPACName=3-Hydroxy-2-phenylpropanoic acid
| OtherNames=2-Phenylhydracrylic acid; Tropate
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=529-64-6
| PubChem=10726
| SMILES=C1=CC=C(C=C1)C(CO)C(=O)O
| EINECS = 209-020-6
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 10274
| InChI = 1/C9H10O3/c10-6-8(9(11)12)7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)
| InChIKey = JACRWUWPXAESPB-UHFFFAOYAV
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C9H10O3/c10-6-8(9(11)12)7-4-2-1-3-5-7/h1-5,8,10H,6H2,(H,11,12)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = JACRWUWPXAESPB-UHFFFAOYSA-N
| RTECS =
| MeSHName = C011377
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = CHEBI:30765
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = C01456
|Section2={{Chembox Properties
| C=9 | H=10 | O=3
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

Tropic acid is a chemical with IUPAC name 3-hydroxy-2-phenylpropanoic acid and condensed structural formula HOCH₂CHPhCOOH. It is a laboratory reagent used in the chemical synthesis of atropine and hyoscyamine. Tropic acid is a chiral substance, existing as either a racemic mixture or as a single enantiomer.

Synthesis

Tropic acid synthesis 1:^[1]	Tropic acid synthesis 2:^[1]

Prepn:^[2]^[3]^[4]

References

1. ^¹{{cite journal|pmid= 12365608|year= 2002|author1= Gadzikowska|first1= M|title= Tropane alkaloical and phytochemical analysis|journal= Acta poloniae pharmaceutica|volume= 59|issue= 2|pages= 149–60|last2= Grynkiewicz|first2= G}}
2. ^Sletzinger, Paulsen, {{US patent|2390278}} (1945 to Merck & Co.).
3. ^Blicke, {{US patent|2716650}} (1955 to University of Michigan).
4. ^{{Cite patent|DE|923426}} (1955 to Sterling Drug).

2 : Beta hydroxy acids|Propionic acids

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。