释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Tubulin beta-4B chain formerly known as tubulin beta-2C chain is a protein that in humans is encoded by the TUBB4B gene.[1][2]References1. ^{{cite journal |vauthors=Lewis SA, Gilmartin ME, Hall JL, Cowan NJ | title = Three expressed sequences within the human beta-tubulin multigene family each define a distinct isotype | journal = J Mol Biol | volume = 182 | issue = 1 | pages = 11–20 |date=Jul 1985 | pmid = 3999141 | pmc = | doi =10.1016/0022-2836(85)90023-3 }} 2. ^{{cite web | title = Entrez Gene: TUBB2C tubulin, beta 2C| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10383| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | author=Burgoyne RD |title=Differential distribution of beta-tubulin isotypes in cerebellum |journal=EMBO J. |volume=7 |issue= 8 |pages= 2311–9 |year= 1989 |pmid= 2461292 |doi= 10.1002/j.1460-2075.1988.tb03074.x| pmc=457095 |name-list-format=vanc| author2=Cambray-Deakin MA | author3=Lewis SA | display-authors=3 | last4=Sarkar | first4=S | last5=Cowan | first5=NJ }}
- {{cite journal |vauthors=Wang D, Villasante A, Lewis SA, Cowan NJ |title=The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype |journal=J. Cell Biol. |volume=103 |issue= 5 |pages= 1903–10 |year= 1987 |pmid= 3782288 |doi=10.1083/jcb.103.5.1903 | pmc=2114403 }}
- {{cite journal | author=Watts NR |title=HIV-1 Rev Depolymerizes Microtubules to Form Stable Bilayered Rings |journal=J. Cell Biol. |volume=150 |issue= 2 |pages= 349–60 |year= 2000 |pmid= 10908577 |doi=10.1083/jcb.150.2.349 | pmc=2180222 |name-list-format=vanc| author2=Sackett DL | author3=Ward RD | display-authors=3 | last4=Miller | first4=M. W. | last5=Wingfield | first5=P. T. | last6=Stahl | first6=S. S. | last7=Steven | first7=A. C. }}
- {{cite journal | author=Szalay J |title=Associations of PKC isoforms with the cytoskeleton of B16F10 melanoma cells |journal=J. Histochem. Cytochem. |volume=49 |issue= 1 |pages= 49–66 |year= 2001 |pmid= 11118478 |doi=10.1177/002215540104900106 |name-list-format=vanc| author2=Bruno P | author3=Bhati R | display-authors=3 | last4=Adjodha | first4=J | last5=Schueler | first5=D | last6=Summerville | first6=V | last7=Vazeos | first7=R }}
- {{cite journal | author=Tarazona R |title=HLA-B2702 (77-83/83-77) peptide binds to beta-tubulin on human NK cells and blocks their cytotoxic capacity |journal=J. Immunol. |volume=165 |issue= 12 |pages= 6776–82 |year= 2001 |pmid= 11120798 |doi= 10.4049/jimmunol.165.12.6776|name-list-format=vanc| author2=López-Lluch G | author3=Galiani MD | display-authors=3 | last4=Aguado | first4=E | last5=Barahona | first5=F | last6=Solana | first6=R | last7=Peña | first7=J }}
- {{cite journal | author=Walss-Bass C |title=Occurrence of nuclear beta(II)-tubulin in cultured cells |journal=Cell Tissue Res. |volume=308 |issue= 2 |pages= 215–23 |year= 2003 |pmid= 12037579 |doi= 10.1007/s00441-002-0539-6 |name-list-format=vanc| author2=Xu K | author3=David S | display-authors=3 | last4=Fellous | first4=Arlette | last5=Ludueña | first5=Richard F. }}
- {{cite journal | author=Krebs DL |title=SOCS-6 Binds to Insulin Receptor Substrate 4, and Mice Lacking the SOCS-6 Gene Exhibit Mild Growth Retardation |journal=Mol. Cell. Biol. |volume=22 |issue= 13 |pages= 4567–78 |year= 2002 |pmid= 12052866 |doi=10.1128/MCB.22.13.4567-4578.2002 | pmc=133908 |name-list-format=vanc| author2=Uren RT | author3=Metcalf D | display-authors=3 | last4=Rakar | first4=S. | last5=Zhang | first5=J.-G. | last6=Starr | first6=R. | last7=De Souza | first7=D. P. | last8=Hanzinikolas | first8=K. | last9=Eyles | first9=J. }}
- {{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}
- {{cite journal |vauthors=Chen D, Wang M, Zhou S, Zhou Q |title=HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim |journal=EMBO J. |volume=21 |issue= 24 |pages= 6801–10 |year= 2004 |pmid= 12486001 |doi=10.1093/emboj/cdf683 | pmc=139103 }}
- {{cite journal | author=Dozier JH |title=β class II tubulin predominates in normal and tumor breast tissues |journal=Breast Cancer Res. |volume=5 |issue= 5 |pages= R157–69 |year= 2003 |pmid= 12927047 |doi= 10.1186/bcr631 | pmc=314434 |name-list-format=vanc| author2=Hiser L | author3=Davis JA | display-authors=3 | last4=Thomas | first4=Nancy | last5=Tucci | first5=Michelle A | last6=Benghuzzi | first6=Hamed A | last7=Frankfurter | first7=Anthony | last8=Correia | first8=John J | last9=Lobert | first9=Sharon }}
- {{cite journal |vauthors=Trinczek B, Brajenovic M, Ebneth A, Drewes G |title=MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes |journal=J. Biol. Chem. |volume=279 |issue= 7 |pages= 5915–23 |year= 2004 |pmid= 14594945 |doi= 10.1074/jbc.M304528200 }}
- {{cite journal | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y | author3=Nishikawa T | display-authors=3 | last4=Otsuki | first4=Tetsuji | last5=Sugiyama | first5=Tomoyasu | last6=Irie | first6=Ryotaro | last7=Wakamatsu | first7=Ai | last8=Hayashi | first8=Koji | last9=Sato | first9=Hiroyuki }}
- {{cite journal | author=Navarro-Lérida I |title=Proteomic identification of brain proteins that interact with dynein light chain LC8 |journal=Proteomics |volume=4 |issue= 2 |pages= 339–46 |year= 2004 |pmid= 14760703 |doi= 10.1002/pmic.200300528 |name-list-format=vanc| author2=Martínez Moreno M | author3=Roncal F | display-authors=3 | last4=Gavilanes | first4=Francisco | last5=Albar | first5=Juan Pablo | last6=Rodríguez-Crespo | first6=Ignacio }}
- {{cite journal | author=Campbell GR |title=The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis |journal=J. Biol. Chem. |volume=279 |issue= 46 |pages= 48197–204 |year= 2005 |pmid= 15331610 |doi= 10.1074/jbc.M406195200 |name-list-format=vanc| author2=Pasquier E | author3=Watkins J | display-authors=3 | last4=Bourgarel-Rey | first4=V | last5=Peyrot | first5=V | last6=Esquieu | first6=D | last7=Barbier | first7=P | last8=De Mareuil | first8=J | last9=Braguer | first9=D }}
- {{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}
- {{cite journal | author=Andersen JS |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 |name-list-format=vanc| author2=Lam YW | author3=Leung AK | display-authors=3 | last4=Ong | first4=Shao-En | last5=Lyon | first5=Carol E. | last6=Lamond | first6=Angus I. | last7=Mann | first7=Matthias }}
- {{cite journal | author=de Mareuil J |title=HIV-1 Tat protein enhances Microtubule polymerization |journal=Retrovirology |volume=2 |issue= |pages= 5 |year= 2006 |pmid= 15691386 |doi= 10.1186/1742-4690-2-5 | pmc=549075 |name-list-format=vanc| author2=Carre M | author3=Barbier P | display-authors=3 | last4=Campbell | first4=Grant R | last5=Lancelot | first5=Sophie | last6=Opi | first6=Sandrine | last7=Esquieu | first7=Didier | last8=Watkins | first8=Jennifer D | last9=Prevot | first9=Charles }}
- {{cite journal | author=Giacca M |title=HIV-1 Tat, apoptosis and the mitochondria: a tubulin link? |journal=Retrovirology |volume=2 |issue= |pages= 7 |year= 2006 |pmid= 15698476 |doi= 10.1186/1742-4690-2-7 | pmc=549042 }}
- {{cite journal |vauthors=Ahmed M, Forsberg J, Bergsten P |title=Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry |journal=J. Proteome Res. |volume=4 |issue= 3 |pages= 931–40 |year= 2005 |pmid= 15952740 |doi= 10.1021/pr050024a }}
{{refend}}External links- {{UCSC genome browser|TUBB4B}}
- {{UCSC gene details|TUBB4B}}
{{PDB Gallery|geneid=10383}}{{gene-9-stub}} |