“Urate-ribonucleotide phosphorylase”的意思、由来-开放百科全书

词条

Urate-ribonucleotide phosphorylase

释义

References

{{enzyme
| Name = urate-ribonucleotide phosphorylase
| EC_number = 2.4.2.16
| CAS_number = 9030-29-9
| IUBMB_EC_number = 2/4/2/16
| GO_code = 0050384
| image =
| width =
| caption =
}}

In enzymology, an urate-ribonucleotide phosphorylase ({{EC number|2.4.2.16}}) is an enzyme that catalyzes the chemical reaction

urate D-ribonucleotide + phosphate urate + alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are urate D-ribonucleotide and phosphate, whereas its two products are urate and alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is urate-ribonucleotide:phosphate alpha-D-ribosyltransferase. Other names in common use include UAR phosphorylase, and urate-ribonucleotide:phosphate D-ribosyltransferase. This enzyme participates in purine metabolism.

References

{{cite journal |author1 = Laster L |author2 =Blair A | date = 1963 | title = An intestinal phosphorylase for uric acid ribonucleoside | journal = J. Biol. Chem. | volume = 238 | pages = 3348–3357 | pmid=14085385}}

2 : EC 2.4.2|Enzymes of unknown structure

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