释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Ubiquitin specific peptidase 5 is an enzyme that in humans is encoded by the USP5 gene.[1][2][3] Interactions USP5 has been shown to interact with TADA3L.[4] References 1. ^{{cite journal | vauthors = Puente XS, Sánchez LM, Overall CM, López-Otín C | title = Human and mouse proteases: a comparative genomic approach | journal = Nature Reviews Genetics | volume = 4 | issue = 7 | pages = 544–58 | date = Jul 2003 | pmid = 12838346 | pmc = | doi = 10.1038/nrg1111 }} 2. ^{{cite journal | vauthors = Ansari-Lari MA, Muzny DM, Lu J, Lu F, Lilley CE, Spanos S, Malley T, Gibbs RA | title = A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13 | journal = Genome Research | volume = 6 | issue = 4 | pages = 314–26 | date = Apr 1996 | pmid = 8723724 | pmc = | doi = 10.1101/gr.6.4.314 }} 3. ^{{cite web | title = Entrez Gene: USP5 ubiquitin specific peptidase 5 (isopeptidase T)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8078| accessdate = }} 4. ^{{cite journal|authorlink30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
Further reading {{refbegin |33em}}- {{cite journal | vauthors = D'Andrea A, Pellman D | title = Deubiquitinating enzymes: a new class of biological regulators | journal = Critical Reviews in Biochemistry and Molecular Biology | volume = 33 | issue = 5 | pages = 337–52 | year = 1999 | pmid = 9827704 | doi = 10.1080/10409239891204251 }}
- {{cite journal | vauthors = Falquet L, Paquet N, Frutiger S, Hughes GJ, Hoang-Van K, Jaton JC | title = cDNA cloning of a human 100 kDa de-ubiquitinating enzyme: the 100 kDa human de-ubiquitinase belongs to the ubiquitin C-terminal hydrolase family 2 (UCH2) | journal = FEBS Letters | volume = 376 | issue = 3 | pages = 233–7 | date = Dec 1995 | pmid = 7498549 | doi = 10.1016/0014-5793(95)01287-7 }}
- {{cite journal | vauthors = Wilkinson KD, Tashayev VL, O'Connor LB, Larsen CN, Kasperek E, Pickart CM | title = Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T | journal = Biochemistry | volume = 34 | issue = 44 | pages = 14535–46 | date = Nov 1995 | pmid = 7578059 | doi = 10.1021/bi00044a032 }}
- {{cite journal | vauthors = Falquet L, Paquet N, Frutiger S, Hughes GJ, Hoang-Van K, Jaton JC | title = A human de-ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro | journal = FEBS Letters | volume = 359 | issue = 1 | pages = 73–7 | date = Feb 1995 | pmid = 7851534 | doi = 10.1016/0014-5793(94)01451-6 }}
- {{cite journal | vauthors = Ansari-Lari MA, Shen Y, Muzny DM, Lee W, Gibbs RA | title = Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination | journal = Genome Research | volume = 7 | issue = 3 | pages = 268–80 | date = Mar 1997 | pmid = 9074930 | doi = 10.1101/gr.7.3.268 }}
- {{cite journal | vauthors = Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S | title = Identification and characterization of the potential promoter regions of 1031 kinds of human genes | journal = Genome Research | volume = 11 | issue = 5 | pages = 677–84 | date = May 2001 | pmid = 11337467 | pmc = 311086 | doi = 10.1101/gr.gr-1640r }}
- {{cite book | vauthors = Engidawork E, Juranville JF, Fountoulakis M, Dierssen M, Lubec G | title = Selective upregulation of the ubiquitin-proteasome proteolytic pathway proteins, proteasome zeta chain and isopeptidase T in fetal Down syndrome | journal = Journal of Neural Transmission. Supplementum | volume = | issue = 61 | pages = 117–30 | year = 2002 | pmid = 11771738 | doi = 10.1007/978-3-7091-6262-0_10 | isbn = 978-3-211-83704-7 }}
- {{cite journal | vauthors = Gabriel JM, Lacombe T, Carobbio S, Paquet N, Bisig R, Cox JA, Jaton JC | title = Zinc is required for the catalytic activity of the human deubiquitinating isopeptidase T | journal = Biochemistry | volume = 41 | issue = 46 | pages = 13755–66 | date = Nov 2002 | pmid = 12427038 | doi = 10.1021/bi026096m }}
- {{cite journal | vauthors = Lacombe T, Gabriel JM | title = Further characterization of the putative human isopeptidase T catalytic site | journal = FEBS Letters | volume = 531 | issue = 3 | pages = 469–74 | date = Nov 2002 | pmid = 12435595 | doi = 10.1016/S0014-5793(02)03586-X }}
- {{cite journal | vauthors = Anderson NL, Polanski M, Pieper R, Gatlin T, Tirumalai RS, Conrads TP, Veenstra TD, Adkins JN, Pounds JG, Fagan R, Lobley A | title = The human plasma proteome: a nonredundant list developed by combination of four separate sources | journal = Molecular & Cellular Proteomics | volume = 3 | issue = 4 | pages = 311–26 | date = Apr 2004 | pmid = 14718574 | doi = 10.1074/mcp.M300127-MCP200 }}
- {{cite journal | vauthors = Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW | title = Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation | journal = Nature Biotechnology | volume = 22 | issue = 6 | pages = 707–16 | date = Jun 2004 | pmid = 15146197 | doi = 10.1038/nbt971 }}
- {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Research | volume = 14 | issue = 7 | pages = 1324–32 | date = Jul 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
- {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
- {{cite journal | vauthors = Reyes-Turcu FE, Horton JR, Mullally JE, Heroux A, Cheng X, Wilkinson KD | title = The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin | journal = Cell | volume = 124 | issue = 6 | pages = 1197–208 | date = Mar 2006 | pmid = 16564012 | doi = 10.1016/j.cell.2006.02.038 }}
{{refend}}{{PDB Gallery|geneid=8078}}{{gene-12-stub}} |