| 词条 | Anserine |
| 释义 |
| Watchedfields = changed | verifiedrevid = 443392191 | ImageFile = Anserine.svg | ImageSize = 220px | IUPACName = (2S)-2-[(3-Amino-1-oxopropyl)amino]-3-(3-methyl-4-imidazolyl)propanoic acid | OtherNames =beta-Alanyl-N(pi)-methyl-L-histidine | Section1 = {{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 100482 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C01262 | InChI = 1/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1 | InChIKey = MYYIAHXIVFADCU-QMMMGPOBBJ | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 448301 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = MYYIAHXIVFADCU-QMMMGPOBSA-N | CASNo_Ref = {{cascite|correct|CAS}} | CASNo=584-85-0 | PubChem=112072 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 18323 | SMILES = O=C(O)[C@@H](NC(=O)CCN)Cc1cncn1C }} | Section2 = {{Chembox Properties | Formula = C10H16N4O3 | MolarMass = 240.25904 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = | Section3 = {{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Anserine (β-alanyl-N-methylhistidine) is a dipeptide containing β-alanine and 1-methylhistidine,[1] which can be found in the skeletal muscle and brain of mammals[2] and birds. The pKa of the imidazole ring of histidine, when contained in anserine, is 7.04, making it an effective buffer at physiologic pH.[3] See also
References1. ^Biochemistry, Garrett & Grisham, pg. 46 {{biochem-stub}}2. ^Quantitative studies of carnosine and anserine in mammalian muscle. 1938 (pdf) 3. ^Biochemistry, Garrett & Grisham 1 : Dipeptides |
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