“Vesicle-fusing ATPase”的意思、由来-开放百科全书

词条

Vesicle-fusing ATPase

释义

References

{{enzyme
| Name = Vesicle-fusing ATPase
| EC_number = 3.6.4.6
| CAS_number =
| IUBMB_EC_number = 3/6/4/6
| GO_code =
| image = 1nsf.jpg
| width = 270
| caption = NSF (= N-ethylmaleimide sensitive factor) hexamer, Hamster
}}

In enzymology, a vesicle-fusing ATPase ({{EC number|3.6.4.6}}) is an enzyme that catalyzes the chemical reaction

ATP + H₂O ADP + phosphate

Thus, the two substrates of this enzyme are ATP and H₂O, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to facilitate cellular and subcellular movement. The systematic name of this enzyme class is ATP phosphohydrolase (vesicle-fusing).

References

{{cite journal |vauthors=Confalonieri F, Duguet M | year = 1995 | title = A 200-amino acid ATPase module in search of a basic function | journal = BioEssays | volume = 17 | pages = 639–50 | pmid = 7646486 | doi = 10.1002/bies.950170710 | issue = 7 }}
{{cite journal |vauthors=Orii T, Kondo N, Osumi T, Fujiki Y | year = 1998 | title = Temperature-sensitive mutation in PEX1 moderates the phenotypes of peroxisome deficiency disorders | journal = Hum. Mol. Genet. | volume = 7 | pages = 2089–94 | pmid = 9817926 | doi = 10.1093/hmg/7.13.2089 | issue = 13 }}
{{cite journal |vauthors=Babst M, Wendland B, Estepa EJ, Emr SD | year = 1998 | title = The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function | journal = EMBO J. | volume = 17 | pages = 2982–93 | pmid = 9606181 | doi = 10.1093/emboj/17.11.2982 | issue = 11 | pmc = 1170638 }}

2 : EC 3.6.4|Enzymes of unknown structure

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