词条 | Vinburnine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 409095415 | IUPAC_name = (3α,16α)-14,15-Dihydroeburnamenin-14-one | image = (all-S)-(–)-Vinburnine Formula V1.svg | tradename = | Drugs.com = {{drugs.com|international|vinburnine}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | IUPHAR_ligand = 345 | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 4880-88-0 | ATC_prefix = C04 | ATC_suffix = AX17 | PubChem = 71203 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 64339 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = G54D0HMY25 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D08676 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1892145 | C=19 | H=22 | N=2 | O=1 | molecular_weight = 294.39 g/mol | synonyms = 3a-Ethyl-2,3,3a,4,10,11b-hexahydro-1H,11H-5a,11a-diaza-benzo[cd]fluoranthen-5-one | smiles = CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2 | StdInChI = 1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChI_comment = | StdInChIKey = WYJAPUKIYAZSEM-MOPGFXCFSA-N | StdInChI_Ref = {{stdinchicite|changed|chemspider}} }}Vinburnine (or eburnamonine, Vincamone) is a vasodilator. Vincamone is a vinca alkaloid and a metabolite of vincamine.[1] References1. ^{{cite journal | pmid = 7192994 | volume=30 | title=Metabolism of vincamine in the rat in vivo and in vitro | journal=Arzneimittelforschung | pages=1860-5 | last1 = Vereczkey | first1 = L | last2 = Tamás | first2 = J | last3 = Czira | first3 = G | last4 = Szporny | first4 = L}} {{Peripheral vasodilators}}{{Xenobiotic-sensing receptor modulators}}{{cardiovascular-drug-stub}} 5 : Vinca alkaloids|Vasodilators|Lactams|Nitrogen heterocycles|Heterocyclic compounds (4 or more rings) |
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