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词条 Vinburnine
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 409095415
| IUPAC_name = (3α,16α)-14,15-Dihydroeburnamenin-14-one
| image = (all-S)-(–)-Vinburnine Formula V1.svg
| tradename =
| Drugs.com = {{drugs.com|international|vinburnine}}
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| IUPHAR_ligand = 345
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 4880-88-0
| ATC_prefix = C04
| ATC_suffix = AX17
| PubChem = 71203
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 64339
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = G54D0HMY25
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08676
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1892145
| C=19 | H=22 | N=2 | O=1
| molecular_weight = 294.39 g/mol
| synonyms = 3a-Ethyl-2,3,3a,4,10,11b-hexahydro-1H,11H-5a,11a-diaza-benzo[cd]fluoranthen-5-one
| smiles = CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=O)C2
| StdInChI = 1S/C19H22N2O/c1-2-19-9-5-10-20-11-8-14-13-6-3-4-7-15(13)21(16(22)12-19)17(14)18(19)20/h3-4,6-7,18H,2,5,8-12H2,1H3/t18-,19+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI_comment =
| StdInChIKey = WYJAPUKIYAZSEM-MOPGFXCFSA-N
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
}}Vinburnine (or eburnamonine, Vincamone) is a vasodilator. Vincamone is a vinca alkaloid and a metabolite of vincamine.[1]

References

1. ^{{cite journal | pmid = 7192994 | volume=30 | title=Metabolism of vincamine in the rat in vivo and in vitro | journal=Arzneimittelforschung | pages=1860-5 | last1 = Vereczkey | first1 = L | last2 = Tamás | first2 = J | last3 = Czira | first3 = G | last4 = Szporny | first4 = L}}
{{Peripheral vasodilators}}{{Xenobiotic-sensing receptor modulators}}{{cardiovascular-drug-stub}}

5 : Vinca alkaloids|Vasodilators|Lactams|Nitrogen heterocycles|Heterocyclic compounds (4 or more rings)

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