词条 | Visnadine |
释义 |
| Watchedfields = changed | verifiedrevid = 443998859 | IUPAC_name = (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2R)-2-methylbutanoate | image = Visnadine.png | tradename = | Drugs.com = {{drugs.com|international|visnadine}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 477-32-7 | ATC_prefix = C04 | ATC_suffix = AX24 | PubChem = 442151 | ChemSpiderID = 390669 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 0RL4V0K263 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D08735 | C=21 | H=24 | O=7 | molecular_weight = 388.41 g/mol | smiles = CC[C@H](C(=O)O[C@H]1[C@@](OC2=C([C@H]1OC(=O)C)C3=C(C=CC(=O)O3)C=C2)(C)C)C | StdInChI = 1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1 | StdInChIKey = GVBNSPFBYXGREE-CXWAGAITSA-N }}Visnadine (or visnadin) is a natural vasodilator.[1] It was first isolated from bishop's weed (Ammi visnaga), a plant indigenous to the Mediterranean region which has been used for centuries in Egypt as a spasmolytic.[2] References1. ^{{cite journal|last=Durate|first=J|author2=Vallejo I |author3=Pérez-Vizcaino F |author4=Jiménez R |author5=Zarzuelo A |author6=Tamargo J |date=1997|title=Effects of visnadine on rat isolated vascular smooth muscles. .|journal=Planta Med|publisher=Thieme Medical Publishers|volume=63|issue=3|pages=233–6|issn=1439-0221|url=http://www.thieme-connect.de/ejournals/abstract/plantamedica/doi/10.1055/s-2006-957660|doi=10.1055/s-2006-957660|pmid=9225605}} {{Peripheral vasodilators}}{{cardiovascular-drug-stub}}2. ^{{cite journal | title = Constitution of Samidin, Dihydrosamidin and Visnadin |author1=Eric Smith |author2=Norman Hosansky |author3=W. G. Bywater |author4=Eugene E. van Tamelen |last-author-amp=yes | journal = J. Am. Chem. Soc. | year = 1957 | volume = 79 | issue = 13 | pages = 3534–3540 | doi = 10.1021/ja01570a062}} 4 : Lactones|Vasodilators|Pyranochromenes|Acetate esters |
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