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词条 Visnadine
释义

  1. References

{{short description|Chemical compound}}{{Drugbox
| Watchedfields = changed
| verifiedrevid = 443998859
| IUPAC_name = (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2R)-2-methylbutanoate
| image = Visnadine.png
| tradename =
| Drugs.com = {{drugs.com|international|visnadine}}
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number = 477-32-7
| ATC_prefix = C04
| ATC_suffix = AX24
| PubChem = 442151
| ChemSpiderID = 390669
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 0RL4V0K263
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08735
| C=21 | H=24 | O=7
| molecular_weight = 388.41 g/mol
| smiles = CC[C@H](C(=O)O[C@H]1[C@@](OC2=C([C@H]1OC(=O)C)C3=C(C=CC(=O)O3)C=C2)(C)C)C
| StdInChI = 1S/C21H24O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h7-11,18-19H,6H2,1-5H3/t11-,18-,19-/m1/s1
| StdInChIKey = GVBNSPFBYXGREE-CXWAGAITSA-N
}}Visnadine (or visnadin) is a natural vasodilator.[1] It was first isolated from bishop's weed (Ammi visnaga), a plant indigenous to the Mediterranean region which has been used for centuries in Egypt as a spasmolytic.[2]

References

1. ^{{cite journal|last=Durate|first=J|author2=Vallejo I |author3=Pérez-Vizcaino F |author4=Jiménez R |author5=Zarzuelo A |author6=Tamargo J |date=1997|title=Effects of visnadine on rat isolated vascular smooth muscles. .|journal=Planta Med|publisher=Thieme Medical Publishers|volume=63|issue=3|pages=233–6|issn=1439-0221|url=http://www.thieme-connect.de/ejournals/abstract/plantamedica/doi/10.1055/s-2006-957660|doi=10.1055/s-2006-957660|pmid=9225605}}
2. ^{{cite journal | title = Constitution of Samidin, Dihydrosamidin and Visnadin |author1=Eric Smith |author2=Norman Hosansky |author3=W. G. Bywater |author4=Eugene E. van Tamelen |last-author-amp=yes | journal = J. Am. Chem. Soc. | year = 1957 | volume = 79 | issue = 13 | pages = 3534–3540 | doi = 10.1021/ja01570a062}}
{{Peripheral vasodilators}}{{cardiovascular-drug-stub}}

4 : Lactones|Vasodilators|Pyranochromenes|Acetate esters

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