| 词条 | (Z)-4-Amino-2-butenoic acid |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | Name = (Z)-4-Amino-2-butenoic acid | verifiedrevid = 477199895 | Reference= [1] | ImageFile=(Z)-4-Amino-2-butenoic_acid.png | ImageFile1 = CACA-3D-balls.png | ImageName1 = C=black, H=white, O=red, N=blue | ImageAlt1 = CACA molecule | PIN = (2Z)-4-Aminobut-2-enoic acid | OtherNames = (Z)-4-Amino-2-butenoic acid cis-4-Aminocrotonic acid 4-Amino-cis-2-butenoic acid |Section1={{Chembox Identifiers | IUPHAR_ligand = 4148 | Abbreviations=CACA | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 5036011 | InChI = 1/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1- | InChIKey = FMKJUUQOYOHLTF-UPHRSURJBR | SMILES1 = O=C(O)\\C=C/CN | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 32307 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C4H7NO2/c5-3-1-2-4(6)7/h1-2H,3,5H2,(H,6,7)/b2-1- | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FMKJUUQOYOHLTF-UPHRSURJSA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo=55199-25-2 | PubChem=6603697 | SMILES=C(\\C=C/C(=O)O)N |Section2={{Chembox Properties | C=4 | H=7 | N=1 | O=2 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility=124 mg/mL |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = | SPhrases = {{S22}} {{S24/25}} }}(Z)-4-Amino-2-butenoic acid[1] (CACA, cis-4-aminocrotonic acid) is a GABA receptor partial agonist selective for the GABA{{sub|A}}-ρ (previously known as GABA{{sub|C}}) subtype.[2][3][4] References1. ^1 cis-4-Aminocrotonic acid at Sigma-Aldrich {{GABAergics}}{{DEFAULTSORT:Amino-2-butenoic acid, (Z)-4-}}{{alkene-stub}}{{nervous-system-drug-stub}}2. ^{{cite journal | last1 = Qian | first1 = H | last2 = Dowling | first2 = JE | title = Selective agonists for GABAC receptors | journal = Trends in Neurosciences | volume = 19 | issue = 5 | pages = 190 | year = 1996 | pmid = 8723205 | doi=10.1016/0166-2236(96)85451-8}} 3. ^{{cite journal | last1 = Duke | first1 = RK | last2 = Chebib | first2 = M | last3 = Balcar | first3 = VJ | last4 = Allan | first4 = RD | last5 = Mewett | first5 = KN | last6 = Johnston | first6 = GA | title = (+)- and (−)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors | journal = Journal of Neurochemistry | volume = 75 | issue = 6 | pages = 2602–10 | year = 2000 | pmid = 11080214 | doi=10.1046/j.1471-4159.2000.0752602.x}} 4. ^{{cite journal | last1 = Reis | first1 = GM | last2 = Duarte | first2 = ID | title = Involvement of chloride channel coupled GABA(C) receptors in the peripheral antinociceptive effect induced by GABA(C) receptor agonist cis-4-aminocrotonic acid | journal = Life Sciences | volume = 80 | issue = 14 | pages = 1268–73 | year = 2007 | pmid = 17316706 | doi = 10.1016/j.lfs.2006.12.015 }} 3 : Amino acids|Alkene derivatives|GABAA-rho receptor agonists |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。