“Z-farnesyl diphosphate synthase”的意思、由来-开放百科全书

词条

Z-farnesyl diphosphate synthase

释义

References

{{enzyme
| Name = Z-farnesyl diphosphate synthase
| EC_number = 2.5.1.68
| CAS_number =
| IUBMB_EC_number = 2/5/1/68
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a Z-farnesyl diphosphate synthase ({{EC number|2.5.1.68}}) is an enzyme that catalyzes the chemical reaction

geranyl diphosphate + isopentenyl diphosphate diphosphate + (2Z,6E)-farnesyl diphosphate

Thus, the two substrates of this enzyme are geranyl diphosphate and isopentenyl diphosphate, whereas its two products are diphosphate and (2Z,6E)-farnesyl diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase. This enzyme is also called (Z)-farnesyl diphosphate synthase.

References

{{cite journal | vauthors = F, Bertini S, Brennan PJ, Crick DC | date = 2001 | title = Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis | journal = J. Biol. Chem. | volume = 276 | pages = 11624–30 | pmid = 11152452 | doi = 10.1074/jbc.M007168200 | issue = 15 }}

2 : EC 2.5.1|Enzymes of unknown structure

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