| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Zinc finger FYVE domain-containing protein 16 is a protein that in humans is encoded by the ZFYVE16 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule (Seet et al., 2004).[supplied by OMIM][2]In melanocytic cells ZFYVE16 gene expression may be regulated by MITF.[3]
}}InteractionsZFYVE16 has been shown to interact with TOM1.[4] References1. ^{{cite journal |vauthors=Seet LF, Hong W | title = Endofin, an endosomal FYVE domain protein | journal = J Biol Chem | volume = 276 | issue = 45 | pages = 42445–54 |date=Nov 2001 | pmid = 11546807 | pmc = | doi = 10.1074/jbc.M105917200 }}
2. ^1 {{cite web | title = Entrez Gene: ZFYVE16 zinc finger, FYVE domain containing 16| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9765| accessdate = }}
3. ^{{cite journal |vauthors=Hoek KS, Schlegel NC, Eichhoff OM, etal | title = Novel MITF targets identified using a two-step DNA microarray strategy | journal = Pigment Cell Melanoma Res. | volume = 21 | issue = 6 | pages = 665–76 | year = 2008 | pmid = 19067971 | doi = 10.1111/j.1755-148X.2008.00505.x }}
4. ^{{cite journal |last=Seet |first=Li-Fong |authorlink= |author2=Liu Ningsheng |author3=Hanson Brendon J |author4=Hong Wanjin |date=Feb 2004 |title=Endofin recruits TOM1 to endosomes |journal=J. Biol. Chem. |volume=279 |issue=6 |pages=4670–9 |publisher= |location = United States| issn = 0021-9258| pmid = 14613930 |doi = 10.1074/jbc.M311228200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Nagase T, Ishikawa K, Nakajima D, etal |title=Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro |journal=DNA Res. |volume=4 |issue= 2 |pages= 141–50 |year= 1997 |pmid= 9205841 |doi=10.1093/dnares/4.2.141 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |bibcode=2002PNAS...9916899M }}
- {{cite journal |vauthors=Seet LF, Liu N, Hanson BJ, Hong W |title=Endofin recruits TOM1 to endosomes |journal=J. Biol. Chem. |volume=279 |issue= 6 |pages= 4670–9 |year= 2004 |pmid= 14613930 |doi= 10.1074/jbc.M311228200 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Brill LM, Salomon AR, Ficarro SB, etal |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763–72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d }}
- {{cite journal |vauthors=Colland F, Jacq X, Trouplin V, etal |title=Functional Proteomics Mapping of a Human Signaling Pathway |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 | pmc=442148 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Rush J, Moritz A, Lee KA, etal |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
- {{cite journal |vauthors=Rual JF, Venkatesan K, Hao T, etal |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |bibcode=2005Natur.437.1173R }}
- {{cite journal |vauthors=Kimura K, Wakamatsu A, Suzuki Y, etal |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129 }}
- {{cite journal |vauthors=Zhao BM, Hoffmann FM |title=Inhibition of Transforming Growth Factor-β1–induced Signaling and Epithelial-to-Mesenchymal Transition by the Smad-binding Peptide Aptamer Trx-SARA |journal=Mol. Biol. Cell |volume=17 |issue= 9 |pages= 3819–31 |year= 2006 |pmid= 16775010 |doi= 10.1091/mbc.E05-10-0990 | pmc=1556379 }}
- {{cite journal |vauthors=Chen YG, Wang Z, Ma J, etal |title=Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling |journal=J. Biol. Chem. |volume=282 |issue= 13 |pages= 9688–95 |year= 2007 |pmid= 17272273 |doi= 10.1074/jbc.M611704200 }}
- {{cite journal |vauthors=Chen Y, Low TY, Choong LY, etal |title=Phosphoproteomics identified Endofin, DCBLD2, and KIAA0582 as novel tyrosine phosphorylation targets of EGF signaling and Iressa in human cancer cells |journal=Proteomics |volume=7 |issue= 14 |pages= 2384–97 |year= 2007 |pmid= 17570516 |doi= 10.1002/pmic.200600968 }}
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