“ZHX2”的意思、由来-开放百科全书

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.^[3]

References

1. ^{{cite journal |vauthors=Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 5 | issue = 6 | pages = 355–64 |date=May 1999 | pmid = 10048485 | pmc = | doi =10.1093/dnares/5.6.355 }}
2. ^{{cite journal |vauthors=Kawata H, Yamada K, Shou Z, Mizutani T, Yazawa T, Yoshino M, Sekiguchi T, Kajitani T, Miyamoto K | title = Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor | journal = Biochem J | volume = 373 | issue = Pt 3 | pages = 747–57 |date=Jul 2003 | pmid = 12741956 | pmc = 1223552 | doi = 10.1042/BJ20030171 }}
3. ^¹{{cite web | title = Entrez Gene: ZHX2 zinc fingers and homeoboxes 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22882| accessdate = }}

Further reading

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}

{{cite journal | author=Kawata H |title=The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3 |journal=Gene |volume=323 |issue= |pages= 133–40 |year= 2004 |pmid= 14659886 |doi=10.1016/j.gene.2003.09.013 |name-list-format=vanc| author2=Yamada K | author3=Shou Z | display-authors=3 | last4=Mizutani | first4=Tetsuya | last5=Miyamoto | first5=Kaoru }}

{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}

{{cite journal | author=Lim J |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 |name-list-format=vanc| author2=Hao T | author3=Shaw C | display-authors=3 | last4=Patel | first4=Akash J. | last5=Szabó | first5=Gábor | last6=Rual | first6=Jean-François | last7=Fisk | first7=C. Joseph | last8=Li | first8=Ning | last9=Smolyar | first9=Alex }}

{{cite journal | author=de Andrade TG |title=Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster |journal=Blood Cells Mol. Dis. |volume=37 |issue= 2 |pages= 82–90 |year= 2006 |pmid= 16952470 |doi= 10.1016/j.bcmd.2006.07.003 |name-list-format=vanc| author2=Peterson KR | author3=Cunha AF | display-authors=3 | last4=Moreira | first4=Luciana Sarmento | last5=Fattori | first5=André | last6=Saad | first6=Sara T.O. | last7=Costa | first7=Fernando Ferreira }}

{{cite journal | author=Liu G |title=ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome |journal=J. Biol. Chem. |volume=281 |issue= 51 |pages= 39681–92 |year= 2007 |pmid= 17056598 |doi= 10.1074/jbc.M606664200 |name-list-format=vanc| author2=Clement LC | author3=Kanwar YS | display-authors=3 | last4=Avila-Casado | first4=C. | last5=Chugh | first5=S. S. }}

{{cite journal | author=Hu S |title=Expression of zinc-fingers and homeoboxes 2 in hepatocellular carcinogenesis: a tissue microarray and clinicopathological analysis |journal=Neoplasma |volume=54 |issue= 3 |pages= 207–11 |year= 2007 |pmid= 17447851 |doi= |name-list-format=vanc| author2=Zhang M | author3=Lv Z | display-authors=3 | last4=Bi | first4=J | last5=Dong | first5=Y | last6=Wen | first6=J }}

See also

References

Further reading