| 词条 | ZNF182 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 |
Model organismsModel organisms have been used in the study of ZNF182 function. A conditional knockout mouse line called Zfp182tm1b(KOMP)Wtsi was generated at the Wellcome Trust Sanger Institute.[5] Male and female animals underwent a standardized phenotypic screen[6] to determine the effects of deletion.[7][8][9][10] Additional screens performed: - In-depth immunological phenotyping[11] - in-depth bone and cartilage phenotyping[12]
References1. ^{{cite journal | vauthors = Knight JC, Grimaldi G, Thiesen HJ, Bech-Hansen NT, Fletcher CD, Coleman MP | title = Clustered organization of Krüppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF21, ZNF41, ZNF81, and ELK1 | journal = Genomics | volume = 21 | issue = 1 | pages = 180–7 | date = May 1994 | pmid = 8088786 | pmc = | doi = 10.1006/geno.1994.1240 }} 2. ^{{cite journal | vauthors = Huebner K, Druck T, Croce CM, Thiesen HJ | title = Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering | journal = American Journal of Human Genetics | volume = 48 | issue = 4 | pages = 726–40 | date = Apr 1991 | pmid = 2014798 | pmc = 1682948 | doi = }} 3. ^{{cite journal | vauthors = Wang R, Cukerman E, Heng HH, Liew CC | title = Localization of a novel zinc finger gene to the human chromosome 7p11.2-p12 by fluorescence in situ hybridization | journal = Somatic Cell and Molecular Genetics | volume = 22 | issue = 3 | pages = 237–9 | date = May 1996 | pmid = 8914609 | pmc = | doi = 10.1007/BF02369914 }} 4. ^{{cite web | title = Entrez Gene: ZNF182 zinc finger protein 182| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7569| accessdate = }} 5. ^{{cite journal |title=The Sanger Mouse Genetics Programme: high throughput characterisation of knockout mice |author=Gerdin AK |year=2010 |journal=Acta Ophthalmologica|volume=88 |pages=925–7|doi=10.1111/j.1755-3768.2010.4142.x }} 6. ^1 {{cite web |url=http://www.mousephenotype.org/data/search?q=Zfp182#fq=**&facet=gene |title=International Mouse Phenotyping Consortium}} 7. ^{{cite journal | vauthors = Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A | title = A conditional knockout resource for the genome-wide study of mouse gene function | journal = Nature | volume = 474 | issue = 7351 | pages = 337–42 | date = Jun 2011 | pmid = 21677750 | pmc = 3572410 | doi = 10.1038/nature10163 }} 8. ^{{cite journal | vauthors = Dolgin E | title = Mouse library set to be knockout | journal = Nature | volume = 474 | issue = 7351 | pages = 262–3 | date = Jun 2011 | pmid = 21677718 | doi = 10.1038/474262a }} 9. ^{{cite journal | vauthors = Collins FS, Rossant J, Wurst W | title = A mouse for all reasons | journal = Cell | volume = 128 | issue = 1 | pages = 9–13 | date = Jan 2007 | pmid = 17218247 | doi = 10.1016/j.cell.2006.12.018 }} 10. ^{{cite journal | vauthors = White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP | title = Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes | journal = Cell | volume = 154 | issue = 2 | pages = 452–64 | date = Jul 2013 | pmid = 23870131 | pmc = 3717207 | doi = 10.1016/j.cell.2013.06.022 }} 11. ^1 {{cite web |url= http://www.immunophenotyping.org/data/search?keys=Zfp182&field_gene_construct_tid=All |title=Infection and Immunity Immunophenotyping (3i) Consortium}} 12. ^1 {{cite web |url=http://www.boneandcartilage.com/ |title=OBCD Consortium}} Further reading{{refbegin | 2}}
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。