| 释义 |
- Clinical significance
- References
- Further reading
- External links
{{Infobox_gene}}Zinc finger protein 202 is a transcription factor first associated with breast cancer. It is a protein that, in humans, is encoded by the ZNF202 gene.[1][2] Clinical significance Variants of this protein have been discovered to be strongly associated with coronary heart disease and atherosclerosis. References 1. ^{{cite journal | vauthors = Monaco C, Helmer Citterich M, Caprini E, Vorechovsky I, Russo G, Croce CM, Barbanti-Brodano G, Negrini M | title = Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins | journal = Genomics | volume = 52 | issue = 3 | pages = 358–62 | date = Sep 1998 | pmid = 9790754 | pmc = | doi = 10.1006/geno.1998.5419 }}
2. ^{{cite web | title = Entrez Gene: ZNF202 zinc finger protein 202| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7753| accessdate = }}
Further reading {{refbegin | 2}}- {{cite book | title=Zinc finger proteins: from atomic contact to cellular function | series=Molecular biology intelligence unit | first1=Shiro | last1=Iuchi | first2=Natalie | last2=Kuldell | publisher=シュプリンガー・ジャパン株式会社 | year=2005 | isbn=0-306-48229-0 | page=161 }}
- {{cite journal | vauthors = Scanlan MJ, Gordan JD, Williamson B, Stockert E, Bander NH, Jongeneel V, Gure AO, Jäger D, Jäger E, Knuth A, Chen YT, Old LJ | title = Antigens recognized by autologous antibody in patients with renal-cell carcinoma | journal = International Journal of Cancer | volume = 83 | issue = 4 | pages = 456–64 | date = Nov 1999 | pmid = 10508479 | doi = 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 }}
- {{cite journal | vauthors = Schumacher C, Wang H, Honer C, Ding W, Koehn J, Lawrence Q, Coulis CM, Wang LL, Ballinger D, Bowen BR, Wagner S | title = The SCAN domain mediates selective oligomerization | journal = The Journal of Biological Chemistry | volume = 275 | issue = 22 | pages = 17173–9 | date = Jun 2000 | pmid = 10747874 | doi = 10.1074/jbc.M000119200 }}
- {{cite journal | vauthors = Wagner S, Hess MA, Ormonde-Hanson P, Malandro J, Hu H, Chen M, Kehrer R, Frodsham M, Schumacher C, Beluch M, Honer C, Skolnick M, Ballinger D, Bowen BR | title = A broad role for the zinc finger protein ZNF202 in human lipid metabolism | journal = The Journal of Biological Chemistry | volume = 275 | issue = 21 | pages = 15685–90 | date = May 2000 | pmid = 10748193 | doi = 10.1074/jbc.M910152199 }}
- {{cite journal | vauthors = Porsch-Ozcurumez M, Langmann T, Heimerl S, Borsukova H, Kaminski WE, Drobnik W, Honer C, Schumacher C, Schmitz G | title = The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux | journal = The Journal of Biological Chemistry | volume = 276 | issue = 15 | pages = 12427–33 | date = Apr 2001 | pmid = 11279031 | doi = 10.1074/jbc.M100218200 }}
- {{cite journal | vauthors = Babb R, Bowen BR | title = SDP1 is a peroxisome-proliferator-activated receptor gamma 2 co-activator that binds through its SCAN domain | journal = The Biochemical Journal | volume = 370 | issue = Pt 2 | pages = 719–27 | date = Mar 2003 | pmid = 12444922 | pmc = 1223195 | doi = 10.1042/BJ20021378 }}
- {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network|authorlink30=Huda Zoghbi | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
- {{cite journal | vauthors = Stene MC, Frikke-Schmidt R, Nordestgaard BG, Steffensen R, Schnohr P, Tybjaerg-Hansen A | title = Zinc Finger Protein 202: a new candidate gene for ischemic heart disease: The Copenhagen City Heart Study | journal = Atherosclerosis | volume = 188 | issue = 1 | pages = 43–50 | date = Sep 2006 | pmid = 16289551 | doi = 10.1016/j.atherosclerosis.2005.10.014 }}
- {{cite journal | vauthors = Stene MC, Frikke-Schmidt R, Nordestgaard BG, Tybjaerg-Hansen A | title = Zinc Finger Protein 202, genetic variation, and HDL cholesterol in the general population | journal = Journal of Lipid Research | volume = 47 | issue = 5 | pages = 944–52 | date = May 2006 | pmid = 16467280 | doi = 10.1194/jlr.M500521-JLR200 }}
{{refend}} External links - {{MeshName|ZNF202+protein,+human}}
{{NLM content}}{{Transcription factors|g2}}{{gene-11-stub}} 3 : Transcription factors|Oncology|Proteins |