释义 |
- Function
- Interactions
- References
- Further reading
- External links
{{Infobox_gene}}Zinc finger protein 238 is a protein that in humans is encoded by the ZNF238 gene.[1][2][3] Function C2H2-type zinc finger proteins, such as ZNF238, act on the molecular level as transcriptional activators or repressors and are involved in chromatin assembly.[supplied by OMIM][3] Interactions ZNF238 has been shown to interact with DNMT3A.[4] References 1. ^{{cite journal | vauthors = Becker KG, Lee IJ, Nagle JW, Canning RD, Gado AM, Torres R, Polymeropoulos MH, Massa PT, Biddison WE, Drew PD | title = C2H2-171: a novel human cDNA representing a developmentally regulated POZ domain/zinc finger protein preferentially expressed in brain | journal = International Journal of Developmental Neuroscience | volume = 15 | issue = 7 | pages = 891–9 | date = November 1997 | pmid = 9568537 | pmc = | doi = 10.1016/S0736-5748(97)00034-8 }} 2. ^{{cite journal | vauthors = Aoki K, Ishida R, Kasai M | title = Isolation and characterization of a cDNA encoding a Translin-like protein, TRAX | journal = FEBS Letters | volume = 401 | issue = 2-3 | pages = 109–12 | date = January 1997 | pmid = 9013868 | pmc = | doi = 10.1016/S0014-5793(96)01444-5 }} 3. ^1 {{cite web | title = Entrez Gene: ZNF238 zinc finger protein 238| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10472| accessdate = }} 4. ^{{cite journal | vauthors = Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T | title = Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription | journal = The EMBO Journal | volume = 20 | issue = 10 | pages = 2536–44 | date = May 2001 | pmid = 11350943 | pmc = 125250 | doi = 10.1093/emboj/20.10.2536 }}
Further reading {{Refbegin | 2}}- {{cite journal | vauthors = Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O | title = Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence | journal = Nature | volume = 377 | issue = 6547 Suppl | pages = 3–174 | date = September 1995 | pmid = 7566098 | doi = | type = PDF }}
- {{cite journal | vauthors = Becker KG, Nagle JW, Canning RD, Biddison WE, Ozato K, Drew PD | title = Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain | journal = Human Molecular Genetics | volume = 4 | issue = 4 | pages = 685–91 | date = April 1995 | pmid = 7633419 | doi = 10.1093/hmg/4.4.685 }}
- {{cite journal | vauthors = Aoki K, Meng G, Suzuki K, Takashi T, Kameoka Y, Nakahara K, Ishida R, Kasai M | title = RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression | journal = The Journal of Biological Chemistry | volume = 273 | issue = 41 | pages = 26698–704 | date = October 1998 | pmid = 9756912 | doi = 10.1074/jbc.273.41.26698 }}
- {{cite journal | vauthors = Ahmad KF, Engel CK, Privé GG | title = Crystal structure of the BTB domain from PLZF | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 95 | issue = 21 | pages = 12123–8 | date = October 1998 | pmid = 9770450 | pmc = 22795 | doi = 10.1073/pnas.95.21.12123 }}
- {{cite journal | vauthors = Meng G, Inazawa J, Ishida R, Tokura K, Nakahara K, Aoki K, Kasai M | title = Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin | journal = Gene | volume = 242 | issue = 1-2 | pages = 59–64 | date = January 2000 | pmid = 10721697 | doi = 10.1016/S0378-1119(99)00477-1 }}
- {{cite journal | vauthors = Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T | title = Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription | journal = The EMBO Journal | volume = 20 | issue = 10 | pages = 2536–44 | date = May 2001 | pmid = 11350943 | pmc = 125250 | doi = 10.1093/emboj/20.10.2536 }}
{{Refend}} External links - {{MeshName|ZNF238+protein,+human}}
{{NLM content}}{{Transcription factors|g2}}{{Gene-1-stub}} 1 : Transcription factors |