| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}Zinc finger protein 274 is a protein that in humans is encoded by the ZNF274 gene.[1][2]{{PBB_Summary
| section_title =
| summary_text = This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.[2]
}}References1. ^{{cite journal | vauthors = Yano K, Ueki N, Oda T, Seki N, Masuho Y, Muramatsu M | title = Identification and characterization of human ZNF274 cDNA, which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability | journal = Genomics | volume = 65 | issue = 1 | pages = 75–80 |date=Jun 2000 | pmid = 10777669 | pmc = | doi = 10.1006/geno.2000.6140 }}
2. ^1 {{cite web | title = Entrez Gene: ZNF274 zinc finger protein 274| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10782| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
- {{cite journal |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 }}
- {{cite journal |vauthors=Petroni D, Bartolini E, Chiaramonte R, etal |title=Computer sequence analysis of human highly conserved zinc finger modules |journal=DNA Seq. |volume=9 |issue= 3 |pages= 163–9 |year= 1999 |pmid= 10520746 |doi= 10.3109/10425179809072191}}
- {{cite journal |vauthors=Casademunt E, Carter BD, Benzel I, etal |title=The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death |journal=EMBO J. |volume=18 |issue= 21 |pages= 6050–61 |year= 2000 |pmid= 10545116 |doi= 10.1093/emboj/18.21.6050 | pmc=1171670 }}
- {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
- {{cite journal |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
- {{cite journal |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
- {{cite journal |vauthors=Wan D, Gong Y, Qin W, etal |title=Large-scale cDNA transfection screening for genes related to cancer development and progression |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101 | pmc=524842 }}
- {{cite journal | vauthors=Sripathy SP, Stevens J, Schultz DC |title=The KAP1 Corepressor Functions To Coordinate the Assembly of De Novo HP1-Demarcated Microenvironments of Heterochromatin Required for KRAB Zinc Finger Protein-Mediated Transcriptional Repression |journal=Mol. Cell. Biol. |volume=26 |issue= 22 |pages= 8623–38 |year= 2007 |pmid= 16954381 |doi= 10.1128/MCB.00487-06 | pmc=1636786 }}
{{refend}} External links - {{MeshName|ZNF274+protein,+human}}
- {{FactorBook|ZNF274}}
{{NLM content}}{{Transcription factors}}{{gene-19-stub}} 1 : Transcription factors |