词条 | Zolimidine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444113320 | ImageFile = Zolimidine.svg | ImageSize = 222 | ImageAlt = Skeletal formula of zolimidine | ImageFile1 = Zolimidine 3D ball.png | ImageSize1 = 240 | ImageAlt1 = Ball-and-stick model of the zolimidine molecule | IUPACName = 2-(4-methylsulfonylphenyl)imidazo[1,2-a]pyridine | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 1222-57-7 | PubChem = 14652 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D07075 | SMILES = CS(=O)(=O)C1=CC=C(C=C1)C2=CN3C=CC=CC3=N2 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 13985 | InChI = 1/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3 | InChIKey = VSLIUWLPFRVCDL-UHFFFAOYAK | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C14H12N2O2S/c1-19(17,18)12-7-5-11(6-8-12)13-10-16-9-3-2-4-14(16)15-13/h2-10H,1H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = VSLIUWLPFRVCDL-UHFFFAOYSA-N | UNII_Ref = {{fdacite|correct|FDA}} | UNII = YCF001N8QB |Section2={{Chembox Properties | Formula = C14H12N2O2S | MolarMass = 272.32 g/mol | Appearance = | Density = 1.31 g/cm3 | MeltingPt = | BoilingPt = | Solubility = |Section6={{Chembox Pharmacology | ATCCode_prefix = A02 | ATCCode_suffix = BX10 }} |Section7={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Zolimidine (zoliridine, brand name Solimidin) is a gastroprotective[1] drug previously used for peptic ulcer[2] and gastroesophageal reflux disease.[3] See also
References1. ^{{cite journal|last1=Parisio|first1=C|last2=Clementi|first2=F|title=Surface Alterations Induced by Stress in Gastric Mucosa: Protective Effect of Zolimidine. A Transmission and Scanning Electron Microscope Investigation|journal=Laboratory Investigation|date=November 1976|volume=35|issue=5|pages=484–95|pmid=136548}} {{Drugs for peptic ulcer and GORD}}{{gastrointestinal-drug-stub}}2. ^{{cite journal|last1=Belohlavek|first1=D|last2=Malfertheiner|first2=P|title=The Effect of Zolimidine, Imidazopyridine-derivate, on the Duodenal Ulcer Healing|journal=Scandinavian Journal of Gastroenterology. Supplement|date=1979|volume=54|pages=44|pmid=161649}} 3. ^{{cite journal|last1=Materia|first1=A|last2=Basso|first2=N|last3=Bagarani|first3=M|last4=Basoli|first4=A|last5=Speranza|first5=V|title=Treatment of Alkaline Reflux Gastritis with Zolimidine. Controlled Study|journal=La Clinica Terapeutica|date=30 April 1981|volume=97|issue=2|pages=183–91|pmid=6453678}} 4 : Abandoned drugs|Drugs for acid-related disorders|Imidazopyridines|Sulfones |
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