“16S rRNA (cytidine1409-2'-O)-methyltransferase”的意思、由来-开放百科全书

词条

16S rRNA (cytidine1409-2'-O)-methyltransferase

释义

References
External links

{{Infobox enzyme
| Name = 16S rRNA (cytidine¹⁴⁰⁹-2'-O)-methyltransferase
| EC_number = 2.1.1.227
| CAS_number =
| IUBMB_EC_number = 2/1/1/227
| GO_code =
| image =
| width =
| caption =
}}16S rRNA (cytidine¹⁴⁰⁹-2'-O)-methyltransferase ({{EC number|2.1.1.227}}, TlyA) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (cytidine¹⁴⁰⁹-2'-O)-methyltransferase.^[1]^[2] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytidine¹⁴⁰⁹ in 16S rRNA S-adenosyl-L-homocysteine + 2'-O-methylcytidine1⁴⁰⁹ in 16S rRNA

The bifunctional enzyme from Mycobacterium tuberculosis.

References

1. ^{{cite journal | vauthors = Johansen SK, Maus CE, Plikaytis BB, Douthwaite S | title = Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs | journal = Molecular Cell | volume = 23 | issue = 2 | pages = 173–82 | date = July 2006 | pmid = 16857584 | doi = 10.1016/j.molcel.2006.05.044 }}
2. ^{{cite journal | vauthors = Maus CE, Plikaytis BB, Shinnick TM | title = Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis | journal = Antimicrobial Agents and Chemotherapy | volume = 49 | issue = 2 | pages = 571–7 | date = February 2005 | pmid = 15673735 | pmc = 547314 | doi = 10.1128/AAC.49.2.571-577.2005 }}

External links

{{MeshName|16S+rRNA+(cytidine1409-2'-O)-methyltransferase}}

1 : EC 2.1.1

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。