Kentucky elected its members August 6, 1810.
| District | Incumbent | This race |
|---|
| Representative | Party | First elected | Results | Candidates |
|---|
| KY|1|X}} | Matthew Lyon | Democratic-Republican | (Vermont)}}
1803 | Incumbent lost re-election.
New member elected.
Democratic-Republican hold. | √ Anthony New (Democratic-Republican) 60.3%
Matthew Lyon (Democratic-Republican) 39.7% |
| KY|2|X}} | Samuel McKee | Democratic-Republican | 1808 | Incumbent re-elected. | √ Samuel McKee (Democratic-Republican) 100% |
| KY|3|X}} | Henry Crist | Democratic-Republican | 1808 | Incumbent retired.
New member elected.
Democratic-Republican hold. | √ Stephen Ormsby (Democratic-Republican)
Philip Quinton{{efn | name="nr" | Numbers of votes missing or incomplete in source}} |
| KY|4|X}} | Richard M. Johnson | Democratic-Republican | 1806 | Incumbent re-elected. | √ Richard M. Johnson (Democratic-Republican){{efn | name="nr"}}
John S. Hunter |
| KY|5|X}} | Benjamin Howard | Democratic-Republican | 1806 | Incumbent resigned April 10, 1810 to become Governor of Louisiana Territory.
New member elected.
Democratic-Republican hold.
Successor was not a candidate to finish the current term, see above. | √ Henry Clay (Democratic-Republican) 100%
|
| KY|6|X}} | Joseph Desha | Democratic-Republican | 1806 | Incumbent re-elected. | √ Joseph Desha (Democratic-Republican) 100% |