Kentucky gained two seats in reapportionment following the 1820 United States Census. Kentucky elected its members August 5, 1822.
| District | Incumbent | This race |
|---|
| Member | Party | First elected | Results | Candidates |
|---|
| KY|1|X}} | David Trimble | Democratic-Republican | 1816 | Incumbent re-elected. | {{Plainlist |- √ David Trimble (Adams-Clay Democratic-Republican) 79.8%
- Thomas Fletcher (Democratic-Republican) 20.2%
}} |
| KY|2|X}} | | {{Small>Redistricted from the {{ushr|KY|4|C}}}}Democratic-Republican | 1818 | Incumbent re-elected. | {{Plainlist |- √ Thomas Metcalfe (Adams-Clay Democratic-Republican) 73.8%
- William Worthington 14.0%
- Walker Reid 12.3%
}} |
| KY|3|X}} | None (District created) | New seat.
New member elected.
Democratic-Republican gain. | {{Plainlist |- √ Henry Clay (Adams-Clay Democratic-Republican) 100%
}} |
| KY|4|X}} | | {{Small>Redistricted from the {{ushr|KY|7|C}}}}Democratic-Republican | 1821 (Special) | Incumbent lost re-election.
New member elected.
Democratic-Republican hold. | {{Plainlist |- √ Robert P. Letcher (Adams-Clay Democratic-Republican) 52.2%
- John S. Smith (Democratic-Republican) 47.8%
}} |
| KY|5|X}} | | {{Small>Redistricted from the {{ushr|KY|3|C}}}}Democratic-Republican | 1820 | Incumbent re-elected. | {{Plainlist |- √ John T. Johnson (Jackson Democratic-Republican) 47.5%{{efn | name="inc" | Based on incomplete data.}}
- Robert McHatton (Jackson Democratic-Republican) 47.8%
- Alfred Sanford 4.7%
}} |
| KY|6|X}} | None (District created) | New seat.
New member elected.
Adams Republican gain. | {{Plainlist |- √ David White (Adams-Clay Democratic-Republican) 56.1%
- John Logan 43.9%
}} |
| KY|7|X}} | | {{Small>Redistricted from the {{ushr|KY|2|C}}}}Democratic-Republican | 1820 | Incumbent lost re-election.
New member elected.
Democratic-Republican hold. | {{Plainlist |- √ Thomas P. Moore (Jackson Democratic-Republican) 41.5%
- John Pope (Democratic-Republican) 29.7%
- Samuel H. Woodson (Democratic-Republican) 28.8%
}} |
| KY|8|X}} | None (District created) | New seat.
New member elected.
Adams Republican gain. | {{Plainlist |- √ Richard A. Bucker (Adams-Clay Democratic-Republican){{efn | name="nr" | Numbers of votes missing or incomplete in source.}}
- Nathan Gaither (Jackson Democratic-Republican?)
}} |
| KY|9|X}} | | {{Small>Redistricted from the {{ushr|KY|8|C}}}}Democratic-Republican | 1821 (Special) | Incumbent lost re-election.
New member elected.
Democratic-Republican hold. | {{Plainlist |- √ Charles A. Wickliffe (Jackson Democratic-Republican) 52.0%
- James D. Breckinridge (Democratic-Republican) 48.0%
}} |
| KY|10|X}} | | {{Small>Redistricted from the {{ushr|KY|6|C}}}}Democratic-Republican | 1820 | Incumbent re-elected. | {{Plainlist |- √ Francis Johnson (Adams-Clay Democratic-Republican) 100%
}} |
| KY|11|X}} | None (District created) | New seat.
New member elected.
Democratic-Republican gain. | {{Plainlist |- √ Philip Thompson (Adams-Clay Democratic-Republican){{efn | name="nr"}}
- James Crutcher
- William Inglish
- John S. Eave
}} |
| KY|12|X}} | None (District created) | New seat.
New member elected.
Democratic-Republican gain. | {{Plainlist |- √ Robert P. Henry (Jackson Democratic-Republican){{efn | Numbers of votes not available in source, said to have won by a majority of 101 votes.}}
- Dickson Given
- Breathitt{{efn | name="fn" | Source does not give full name.}}
- Young Ewing
}} |