2010–11 runner-up Team Tvis Holstebro defeated Metz HB in the final overcoming a home 4-goals loss to win its first international trophy and the third win for Denmark in four years. They previously defeated defending champion Lada Togliatti in the round of 16 and FC Midtjylland, which defeated them in the 2011 final, in the semifinals. Metz, which defeated the previous season's runner-up HC Zalău in the semifinals, was the first French team to reach the competition's final since 1993.
Team #1 | Agg. | Team #2 | 1st match | 2nd match | Megas Alexandros {{flagicon|GRE}} | 49–49 | {{flagicon|Kosovo}} Prishtina | 27–27 | 22–22 |
Gorodnichanka {{flagicon|BLR}} | 48–77 | {{flagicon|HUN}} Érdi | 25–46 | 23–31 |
Dunarea Braila {{flagicon|ROM}} | 72–29 | {{flagicon|Montenegro}} Biseri Pljevlja | 39–14 | 33–15 |
Teramo {{flagicon|ITA}} | 0–20 | {{flagicon|ESP}} Alcobendas | 0–10 | 0–10 |
Tvis Holstebro {{flagicon|DEN}} | 96–47 | {{flagicon|BIH}} Borac Banja Luka | 54–22 | 42–25 |
Maccabi Ramat Gan {{flagicon|ISR}} | 44–82 | {{flagicon|BEL}} Fémina Visé | 21–41 | 23–41 |
Valencia Aicequip {{flagicon|ESP}} | 47–64 | {{flagicon|ISL}} Valur | 22–27 | 25–37 |
Zaglebie Lubin {{flagicon|POL}} | 43–37 | {{flagicon|CRO}} Zelina | 22–18 | 21–19 |
Tertnes {{flagicon|NOR}} | 53–42 | {{flagicon|ISL}} Fram | 35–21 | 18–21 |
Sassari {{flagicon|ITA}} | 63–49 | {{flagicon|ISR}} Bnei Herzliya | 30–24 | 33–25 |
HC Karpaty Uzhgorod {{flagicon|UKR}} | 74–45 | {{flagicon|BUL}} Etar Veliko Tarnovo | 34–17 | 40–28 |
Sokol Poruba {{flagicon|CZE}} | 52–59 | {{flagicon|RUS}} Astrakhanochka | 23–23 | 29–36 |
Team #1 | Agg. | Team #2 | 1st match | 2nd match | Juve Lis {{flagicon|POR}} | 49–48 | {{flagicon|SWI}} Spono Nottwil | 24–26 | 25–22 |
Érdi {{flagicon|HUN}} | 63–63 | {{flagicon|FRA}} Metz | 37–31 | 26–32 |
Sassari {{flagicon|ITA}} | 0–20 | {{flagicon|RUS}} Lada Togliatti | 0–10 | 0–10 |
Zaglebie Lubin {{flagicon|POL}} | 55–53 | {{flagicon|BLR}} BNTU Minsk | 30–29 | 25–24 |
Alcobendas {{flagicon|ESP}} | 32–74 | {{flagicon|DEN}} Midtjylland | 14–37 | 18–37 |
Valur {{flagicon|ISL}} | 45–45 | {{flagicon|ROM}} Zalau | 24–23 | 21–22 |
Astrakhanochka {{flagicon|RUS}} | 63–59 | {{flagicon|HUN}} Siófok | 41–28 | 22–31 |
Itxako {{flagicon|ESP}} | 73–41 | {{flagicon|CYP}} Latsia | 33–23 | 40–18 |
HC Karpaty Uzhgorod {{flagicon|UKR}} | 54–55 | {{flagicon|SRB}} Radnički Kragujevac | 31–22 | 23–33 |
Lugi {{flagicon|SWE}} | 50–72 | {{flagicon|DEN}} Tvis Holstebro | 24–39 | 26–33 |
Zagorje {{flagicon|SVN}} | 69–40 | {{flagicon|Kosovo}} Prishtina | 43–22 | 26–18 |
Patras {{flagicon|GRE}} | 35–55 | {{flagicon|MKD}} Vardar Skopje | 19–28 | 16–27 |
Kuban Krasnodar {{flagicon|RUS}} | 52–51 | {{flagicon|ROM}} Dunarea Braila | 28–22 | 24–29 |
Westfriesland {{flagicon|NED}} | 37–69 | {{flagicon|FRA}} Le Havre | 22–38 | 15–31 |
Cankaya {{flagicon|TUR}} | 73–46 | {{flagicon|BEL}} Fémina Visé | 31–21 | 42–25 |
Tertnes {{flagicon|NOR}} | 64–58 | {{flagicon|GER}} Frankfurter | 34–22 | 30–36 |
Team #1 | Agg. | Team #2 | 1st match | 2nd match | Astrakhanochka {{flagicon|RUS}} | 78–50 | {{flagicon|SRB}} Radnički Kragujevac | 41–25 | 37–25 |
Cankaya {{flagicon|TUR}} | 60–60 | {{flagicon|ESP}} Itxako | 37–24 | 23–36 |
Tertnes {{flagicon|NOR}} | 64–51 | {{flagicon|FRA}} Le Havre | 33–23 | 31–28 |
Zalau {{flagicon|ROM}} | 54–22 | {{flagicon|POR}} Juve Lis | 25–14 | 29–8 |
Vardar Skopje {{flagicon|MKD}} | 47–50 | {{flagicon|RUS}} Kuban Krasnodar | 30–28 | 17–22 |
Tvis Holstebro {{flagicon|DEN}} | 54–49 | {{flagicon|RUS}} Lada Togliatti | 24–19 | 30–30 |
Midtjylland {{flagicon|DEN}} | 59–50 | {{flagicon|SVN}} Zagorje | 31–28 | 28–22 |
Metz {{flagicon|FRA}} | 53–50 | {{flagicon|POL}} Zaglebie Lubin | 29–28 | 24–22 |
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1. ^Women's EHF Cup draw results. EHF
{{EHF Cup seasons}}{{2012–13 in European handball (EHF)}}{{2012–13 European club competitions}}{{DEFAULTSORT:2012-13 Women's EHF Cup}}