“23S rRNA (adenine1618-N6)-methyltransferase”的意思、由来-开放百科全书

词条

23S rRNA (adenine1618-N6)-methyltransferase

释义

References
External links

{{Infobox enzyme
| Name = 23S rRNA (adenine¹⁶¹⁸-N⁶)-methyltransferase
| EC_number = 2.1.1.181
| CAS_number =
| IUBMB_EC_number = 2/1/1/181
| GO_code =
| image =
| width =
| caption =
}}23S rRNA (adenine¹⁶¹⁸-N⁶)-methyltransferase ({{EC number|2.1.1.181}}, rRNA large subunit methyltransferase F, YbiN protein, rlmF (gene), m6A1618 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (adenine¹⁶¹⁸-N⁶)-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine¹⁶¹⁸ in 23S rRNA S-adenosyl-L-homocysteine + N⁶-methyladenine¹⁶¹⁸ in 23S rRNA

The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit.

References

1. ^{{cite journal | vauthors = Sergiev PV, Serebryakova MV, Bogdanov AA, Dontsova OA | title = The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel | journal = Journal of Molecular Biology | volume = 375 | issue = 1 | pages = 291–300 | date = January 2008 | pmid = 18021804 | doi = 10.1016/j.jmb.2007.10.051 }}

External links

{{MeshName|23S+rRNA+(adenine1618-N6)-methyltransferase}}

1 : EC 2.1.1

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