词条 | 25N-NBOMe |
释义 |
| ImageFile = 25N-NBOMe_structure_300px.png | ImageSize = 200px | IUPACName = 2-(2,5-Dimethoxy-4-nitrophenyl)-N-(2-methoxybenzyl)ethanamine | OtherNames = 2C-N-NBOMe, NBOMe-2C-N | Section1 = {{Chembox Identifiers | CASNo = 1354632-03-3 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 0G7SSW2N0S | PubChem = 118536028 | ChemSpiderID = 52085577 | SMILES = COC1=C(CCNCC2=C(OC)C=CC=C2)C=C(OC)C([N+]([O-])=O)=C1 | StdInChI = 1S/C18H22N2O5/c1-23-16-7-5-4-6-14(16)12-19-9-8-13-10-18(25-3)15(20(21)22)11-17(13)24-2/h4-7,10-11,19H,8-9,12H2,1-3H3 | StdInChIKey = TXCKTIBHURMASQ-UHFFFAOYSA-N }} | Section2 = {{Chembox Properties | C=18 | H=22 | N=2 | O=5 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} | Section3 = {{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}25N-NBOMe (2C-N-NBOMe, NBOMe-2C-N) is a derivative of the hallucinogen 2C-N. The pharmacological properties of 25N-NBOMe have not been described in the scientific literature, but it is believed to act in a similar manner to related compounds such as 25I-NBOMe and 25C-NBOMe, which are potent agonists at the 5HT2A receptor.[1][2] 25N-NBOMe has been sold as a street drug and has only been described in the literature in terms of identification by forensic analysis.[3][4] Legality25N-NBOMe is illegal in Alabama,[5] and Hungary.[6] SwedenThe Riksdag added 25N-NBOMe to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of January 16, 2015, published by Medical Products Agency (MPA) in regulation LVFS 2014:11 listed as 25N-NBOMe, and 2-(2,5-dimetoxi-4-nitrofenyl)-N-(2-metoxibensyl)etanamin.[7]United Kingdom{{N-benzylphenethylamine-Legality-United Kingdom}}See also
References1. ^{{Cite journal | last1 = Hansen | first1 = M. | last2 = Phonekeo | first2 = K. | last3 = Paine | first3 = J. S. | last4 = Leth-Petersen | first4 = S. | last5 = Begtrup | first5 = M. | last6 = Bräuner-Osborne | first6 = H. | last7 = Kristensen | first7 = J. L. | doi = 10.1021/cn400216u | title = Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2C Agonists | journal = ACS Chemical Neuroscience | volume = 5 | issue = 3 | pages = 243–9 | year = 2014 | pmid = 24397362| pmc = 3963123}} {{Hallucinogens}}{{Serotonin receptor modulators}}{{Phenethylamines}}{{hallucinogen-stub}}2. ^Hansen, M. Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain. PhD Thesis, University of Copenhagen, 2011. 3. ^{{cite journal|last=Casale|first=John F.|author2=Hays, Patrick A.|title=Characterization of Eleven 2,5-Dimethoxy-N-(2-methoxybenzyl)phenethylamine (NBOMe) Derivatives and Differentiation from their 3- and 4-Methoxybenzyl Analogues - Part I|journal=Microgram Journal|year=2012|volume=9|issue=2|pages=84–109|url=http://www.justice.gov/dea/pr/microgram-journals/2012/mj9_84-109.pdf|accessdate=14 January 2014}} 4. ^{{cite journal | title=Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products |vauthors=Uchiyama N, Shimokawa Y, Matsuda S, Kawamura M, Kikura-Hanajiri R, Goda Y | journal=Forensic Toxicology | year=2014 | volume=32 | issue=1 | pages=105–115 | doi=10.1007/s11419-013-0217-2}} 5. ^[https://legiscan.com/AL/text/SB333/id/988417/Alabama-2014-SB333-Enrolled.pdf Alabama Senate Bill SB 333: Controlled Substances] 6. ^A Daath.hu kiegészítése a BSZKI "designer jogi listáján" nem szereplő, de az UP jegyzék 1.-4. szerkezeti leírásainak megfelelő, illetve az 5. felsorolásában szereplő néhány anyagról 7. ^https://lakemedelsverket.se/upload/lvfs/LVFS_2014_11.pdf 3 : 25-NB (psychedelics)|Nitro compounds|Designer drugs |
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