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词条 2'''-acetyl-6'''-hydroxyneomycin C deacetylase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = 2'''-acetyl-6'''-hydroxyneomycin C deacetylase
| EC_number = 3.5.1.113
| CAS_number =
| IUBMB_EC_number = 3/5/1/113
| GO_code =
| image =
| width =
| caption =
}}2'''-acetyl-6'''-hydroxyneomycin C deacetylase ({{EC number|3.5.1.113}}, neoL (gene)) is an enzyme with systematic name 2'''-acetyl-6'''-hydroxyneomycin C hydrolase (acetate-forming).[1] This enzyme catalyses the following chemical reaction

2'''-acetyl-6'''-deamino-6'''-hydroxyneomycin C + H2O 6'''-deamino-6'''-hydroxyneomycin C + acetate

This enzyme is involved in biosynthesis of aminoglycoside antibiotics of the [neomycin] family.

References

1. ^{{cite journal | vauthors = Yokoyama K, Yamamoto Y, Kudo F, Eguchi T | title = Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis | journal = ChemBioChem | volume = 9 | issue = 6 | pages = 865–9 | date = April 2008 | pmid = 18311744 | doi = 10.1002/cbic.200700717 }}

External links

  • {{MeshName|{{urlencode:2-acetyl-6-hydroxyneomycin C deacetylase}}|3=2'''-acetyl-6'''-hydroxyneomycin C deacetylase}}
{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.5.1

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