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词条 2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = 2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase
| EC_number = 2.1.1.201
| CAS_number =
| IUBMB_EC_number = 2/1/1/201
| GO_code =
| image =
| width =
| caption =
}}2-Methoxy-6-polyprenyl-1,4-benzoquinol methylase ({{EC number|2.1.1.201}}, ubiE (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol 5-C-methyltransferase.[1][2][3][4] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol S-adenosyl-L-homocysteine + 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol

This enzyme is involved in ubiquinone biosynthesis.

References

1. ^{{cite journal | vauthors = Lee PT, Hsu AY, Ha HT, Clarke CF | title = A C-methyltransferase involved in both ubiquinone and menaquinone biosynthesis: isolation and identification of the Escherichia coli ubiE gene | journal = Journal of Bacteriology | volume = 179 | issue = 5 | pages = 1748–54 | date = March 1997 | pmid = 9045837 | pmc = 178890 | doi = 10.1128/jb.179.5.1748-1754.1997 }}
2. ^{{cite journal | vauthors = Young IG, McCann LM, Stroobant P, Gibson F | title = Characterization and genetic analysis of mutant strains of Escherichia coli K-12 accumulating the biquinone precursors 2-octaprenyl-6-methoxy-1,4-benzoquinone and 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone | journal = Journal of Bacteriology | volume = 105 | issue = 3 | pages = 769–78 | date = March 1971 | pmid = 4323297 | pmc = 248499 }}
3. ^{{cite journal | vauthors = Dibrov E, Robinson KM, Lemire BD | title = The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain | journal = The Journal of Biological Chemistry | volume = 272 | issue = 14 | pages = 9175–81 | date = April 1997 | pmid = 9083048 | doi = 10.1074/jbc.272.14.9175 }}
4. ^{{cite journal | vauthors = Barkovich RJ, Shtanko A, Shepherd JA, Lee PT, Myles DC, Tzagoloff A, Clarke CF | title = Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis | journal = The Journal of Biological Chemistry | volume = 272 | issue = 14 | pages = 9182–8 | date = April 1997 | pmid = 9083049 | doi = 10.1074/jbc.272.14.9182 }}

External links

  • {{MeshName|2-methoxy-6-polyprenyl-1,4-benzoquinol+methylase}}
{{One carbon transferases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 2.1.1

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