| Best Actor in leading role |
| Winners | Agency | Characters | Anime |
|---|
| Mamoru Miyano | Himawari Theatre Group | Setsuna F. Seiei
Hakugen Rikuson | Mobile Suit Gundam 00
Koutetsu Sangokushi |
| Best Actress in leading role |
| Aya Hirano | Space Craft | Konata Izumi
Reira Serizawa
Misa Amane
| Lucky Star
Nana
Death Note |
| Best Actors in supporting roles |
| Daisuke Ono | Mausu Promotion | Hosaka
Kagezaki | Minami-ke
Rental Magica |
| Hiroshi Kamiya | Aoni Production | Tieria Erde
Nozomu Itoshiki | Mobile Suit Gundam 00
Sayonara Zetsubō Sensei |
| Best Actresses in supporting roles |
| Rie Kugimiya | I'm Enterprise | Nagi Sanzenin
Shana | Hayate the Combat Butler
Shakugan no Shana |
| Mitsuki Saiga | Ken Production | Kei Yūki
Rossiu
Jomy Marcus Shin | Moyashimon
Tengen Toppa Gurren Lagann
Toward the Terra |
| Best Rookie actors |
| Wataru Hatano | 81 Produce | Sam Houston
Tenshi Yuri | Toward the Terra
Saint Beast: Kouin Jojishi Tenshi Tan |
| Tsubasa Yonaga | Ken Production | Ren Mihashi
Shingo Suwa | Ookiku Furikabutte
Kishin Taisen Gigantic Formula |
| Best Rookie actresses |
| Emiri Kato | 81 Produce | Momoko Akatsutsumi/Hyper Blossom
Kagami Hiiragi | Demashita! Powerpuff Girls Z
Lucky Star |
| Yu Kobayashi | Holy Peak | Sarutobi Ayame
Kaere Kimura | Gintama
Sayonara Zetsubō Sensei |
| Best Personality |
| Winner | Agency | Radio Program | Broadcasting Station |
|---|
| Kenichi Suzumura | Arts Vision | Cherry Bell | JOQR |
| Best Musical Performance |
| Winners | Record Label | Song | Anime |
|---|
| Aya Hirano, Emiri Kato, Kaori Fukuhara, Aya Endo | Lantis | Motteke! Sailor Fuku, opening theme | Lucky Star |
| Special Achievement Award |
| Winners | Agency |
|---|
| Tatsuya Jo | Haikyō (final career) |
| Achievement Award |
| Nachi Nozawa | Ken Production |
| Michio Hazama | Mouvement |
| Ryoko Kinomiya | Haikyō |
| Synergy Award |
| Kamen Rider Den-O (Toshihiko Seki, Koji Yusa, Masaki Terasoma & Kenichi Suzumura) |
| Kei Tomiyama Memorial Award (Topical Award) |
| Toru Furuya | Aoni Production |
|
1. ^{{cite web |url= http://www.animenewsnetwork.com/news/2008-03-09/2nd-annual-seiyu-awards-announced|title= 2nd Annual Seiyū Awards Announced|date=2008-03-09|accessdate= 2012-09-30|work= Anime News Network}}
{{Seiyu Awards}}