| 词条 | 4-HO-DSBT |
| 释义 |
| IUPAC_name = 3-[2-[di(butan-2-yl)amino]ethyl]-1H-indol-4-ol | image = 4-HO-DSBT.png | width = 240 | tradename = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 127507-01-1 | CAS_supplemental =77872-40-3 (hydrochloride) | ChemSpiderID = 10513070 | PubChem = 21786580 | C=18 | H=28 | N=2 | O=1 | molecular_weight = 288.43 g/mol | smiles = CCC(C)N(CCc1c[nH]c2cccc(O)c12)C(C)CC | StdInChI = 1S/C18H28N2O/c1-5-13(3)20(14(4)6-2)11-10-15-12-19-16-8-7-9-17(21)18(15)16/h7-9,12-14,19,21H,5-6,10-11H2,1-4H3 | StdInChIKey = SMKFHUHBZWMALV-UHFFFAOYSA-N }}4-HO-DSBT (4-hydroxy-N,N-di-sec-butyltryptamine) is a tryptamine derivative which acts as a serotonin receptor agonist. It was first made by Alexander Shulgin and is mentioned in his book TiHKAL, but was never tested by him.[1] However it has subsequently been tested in vitro and unlike the n-butyl and isobutyl isomers which are much weaker, the s-butyl derivative retains reasonable potency, with a similar 5-HT2A receptor affinity to MiPT but better selectivity over the 5-HT1A and 5-HT2B subtypes.[2] See also
References1. ^4-HO-DBT TiHKAL entry {{TiHKAL}}{{Serotonergics}}{{Tryptamines}}{{Pharm-stub}}2. ^{{Cite journal | last1 = McKenna | first1 = D. J. | last2 = Repke | first2 = D. B. | last3 = Lo | first3 = L. | last4 = Peroutka | first4 = S. J. | title = Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes | doi = 10.1016/0028-3908(90)90001-8 | journal = Neuropharmacology | volume = 29 | issue = 3 | pages = 193–198 | year = 1990 | pmid = 2139186| pmc = }} 1 : Tryptamines |
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