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词条 4-hydroxybutanoyl-CoA dehydratase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = 4-hydroxybutanoyl-CoA dehydratase
| EC_number = 4.2.1.120
| CAS_number =
| IUBMB_EC_number = 4/2/1/120
| GO_code =
| image =
| width =
| caption =
}}4-hydroxybutanoyl-CoA dehydratase ({{EC number|4.2.1.120}}) is an enzyme with systematic name 4-hydroxybutanoyl-CoA hydro-lyase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

4-hydroxybutanoyl-CoA but-3-enoyl-CoA + H2O

This enzyme contains FAD and a [4Fe-4S] iron-sulfur cluster.

References

1. ^{{cite journal | title = A vinylacetyl isomerase from Clostridium kluyveri |author1 = Bartsch, R.G. |author2 =Barker, H.A. |journal = Arch. Biochem. Biophys. |year = 1961 |volume = 92 |pages = 122–132 |pmid = 13687513 |doi=10.1016/0003-9861(61)90226-0}}
2. ^{{cite journal | title = Succinate-ethanol fermentation in Clostridium kluyveri: purification and characterisation of 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ32-isomerase |author1 = Scherf, U. |author2 =Sohling, B. |author3 =Gottschalk, G. |author4 =Linder, D. |author5 =Buckel, W. |journal = Arch. Microbiol. |year = 1994 |volume = 161 |pages = 239–245 |pmid = 8161284 |issue=3 |doi=10.1007/bf00248699}}
3. ^{{cite journal | title = Purification and properties of an iron-sulfur and FAD-containing 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA Δ32-isomerase from Clostridium aminobutyricum |author1 = Scherf, U. |author2 =Buckel, W. |journal = Eur. J. Biochem. |year = 1993 |volume = 215 |pages = 421–429 |pmid = 8344309 |issue=2 |doi=10.1111/j.1432-1033.1993.tb18049.x}}
4. ^{{cite journal | title = 4-Hydroxybutyryl-CoA dehydratase from Clostridium aminobutyricum: characterization of FAD and iron-sulfur clusters involved in an overall non-redox reaction |author1 = Muh, U. |author2 =Cinkaya, I. |author3 =Albracht, S.P. |author4 =Buckel, W. |journal = Biochemistry |year = 1996 |volume = 35 |pages = 11710–11718 |pmid = 8794752 |doi=10.1021/bi9601363 |issue=36}}
5. ^{{cite journal | title = A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea |author1 = Berg, I.A. |author2 =Kockelkorn, D. |author3 =Buckel, W. |author4 =Fuchs, G. |journal = Science |year = 2007 |volume = 318 |pages = 1782–1786 |pmid = 18079405 |doi=10.1126/science.1149976}}

External links

  • {{MeshName|4-hydroxybutanoyl-CoA+dehydratase}}
{{Carbon-oxygen lyases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 4.2.1

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